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Heat zaps tiny thyroid tumors, no scalpel needed

NCT ID NCT07506161

Disease control Sponsor: Premier G Med Cardio Kft Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a procedure called radiofrequency ablation, which uses heat to destroy small thyroid cancers. 27 adults with low-risk papillary thyroid microcarcinoma who did not want surgery or active monitoring took part. The goal was to see if the treatment could eliminate the tumor and keep it from coming back, while tracking any side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

27 people

The number who actually took part.

Started

Sep 2021

Finished

Dec 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All participants are of Hungarian nationality, treated and controlled in the PremierMed Center in Budapest with cytologically confirmed papillary thyroid microcarcinoma

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients with cytologically confirmed papillary thyroid carcinoma with the longest diameter of less than or equal to 10 mms in T1aN0M0 clinical stage without metastases and without cytological signs of aggressivity AND * Patients objecting to both surgery and active surveillance Exclusion Criteria: * History of or active disease: neck irradiation, stroke, CV disease, CNS vascular malformation, any malignant disease, immunocompromised state, recurrent laryngeal nerve paresis, organ failure * extrathyroidal extension of tumor (including capsular) * pregnancy * lesion less than 5 mm close to the danger zone * safety margin could not be obtained (min 2mm) * uncontrolled hyperthyroidism * uncontrolled hypothyroidism * primary hyperparathyroidism * calcitonin or serum calcium over the threshold on a repeat blood test

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Conditions

The condition(s) this trial relates to.

papillary thyroid Microcarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Papillary thyroid microcarcinoma

Contacts and locations

Locations

  • Premier Med Egészségügyi- Oktató- és Kutatóintézet

    Budapest, 1037, Hungary

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