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New hope for PBC itch: experimental drug TH104 enters Mid-Stage trial

NCT ID NCT06733519

First seen Nov 01, 2025 · Last updated May 18, 2026 · Updated 33 times

Summary

This study tests an experimental drug called TH104 for people with primary biliary cholangitis (PBC) who suffer from moderate to severe itching. The trial will include 40 adults aged 18 to 75 and aims to see if the drug is safe and tolerable. Participants will be randomly assigned to receive either TH104 or a placebo, and researchers will track side effects and changes in itch scores.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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