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Cheap Blood-Fat indexes may spot insulin resistance without fancy lab tests

NCT ID NCT07260201

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether two simple, low-cost blood-fat indexes (TGI and TGI-BMI) can accurately detect insulin resistance, compared to the standard HOMA-IR test that requires a fasting insulin measurement. Researchers analyzed data from 150 adults without diabetes medications. They found both indexes worked well, especially the TGI-BMI in people with obesity. If confirmed, these indexes could make insulin resistance screening more accessible in everyday clinics.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If validated, these simple blood-fat indexes could replace costly insulin tests, making insulin resistance screening easier and cheaper in routine clinics.
What could go wrong
This is a small, retrospective study (150 people) that only compares indexes to HOMA-IR, not to hard outcomes like diabetes development. Results may not apply to people on diabetes medications or with other health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

150 people

The number who actually took part.

Started

Dec 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients who underwent routine biochemical testing and metabolic evaluation at Hisar Intercontinental Hospital. Data were obtained retrospectively from medical records. Participants were divided into two cohorts based on insulin resistance status determined by HOMA-IR values: Non-Insulin Resistant (HOMA-IR \< 2.5) Insulin Resistant (HOMA-IR \> 2.5)

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Eligible participants were adults aged 18-65 years with complete fasting biochemical and anthropometric data. Only patients who were not receiving antidiabetic medications at the time of evaluation were included. Exclusion Criteria: * Patients were excluded if they had any of the following: * Known endocrine disorders (e.g., thyroid dysfunction, Cushing's syndrome) * Chronic kidney or liver disease * Active infection or systemic inflammatory disease * Ongoing use of medications known to affect glucose or lipid metabolism (e.g., corticosteroids, statins, metformin, or insulin) * Incomplete or missing laboratory data

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Conditions

The condition(s) this trial relates to.

Insulin Resistance type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hisar Intercontinental Hospital

    Istanbul, Umraniye, 34768, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.