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New nerve block may cut opioid use after gynecologic surgery

NCT ID NCT06847022

Symptom relief Sponsor: Thammasat University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a specific nerve block called transversalis fascia plane block (TFPB) can reduce pain and the need for morphine after open gynecologic surgery. Thirty-two adults received the block with bupivacaine after their incision was closed. Researchers measured morphine use over 24 hours and checked for side effects and chronic pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If effective, this nerve block could become a standard way to reduce pain and opioid use after gynecologic surgery.
What could go wrong
This is a small, single-center study with only 32 participants. Results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Nov 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who undergoing open gynecologic surgery under general anesthesia * Age 18 - 70 years * ASA Physical status I-III * Transverse incision Exclusion Criteria: * Creatinine clearance is less than 30 ml/min * Body weight \< 50 kg * Re-open surgery * Persistent chronic pelvic pain * Allergic to medications used in this study

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gynecologic surgical procedures Transversalis fascia plane block

Contacts and locations

Locations

  • Department of Anesthesiology, Faculty of Medicine, Thammasat University

    Pathum Thani, 12121, Thailand

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