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Teens' PTSD symptoms tracked during therapy: a closer look at individual progress

NCT ID NCT07402681

Knowledge-focused Sponsor: University Children's Hospital, Zurich Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 21 adolescents aged 12 to 18 who have experienced trauma and are undergoing trauma-focused cognitive behavioral therapy (TF-CBT). Researchers will regularly measure their PTSD symptoms, along with anxiety and depression, to see how symptoms change over time. The goal is to better understand individual patterns of improvement, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Trauma-focused cognitive behavioral therapy (TF-CBT)
What this could lead to
If successful, this could help therapists better tailor TF-CBT to individual teens by understanding how symptoms change during treatment.
What could go wrong
This is a small observational study with only 21 participants, so results may not apply to all teens. It measures symptoms but does not test if the therapy works better than other approaches.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 21 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adolescents between 12 and 18 years for whom trauma-focused treatment is indicated due to a PTE/ PTEs they have experienced as well as a significant level of PTSS.

Ages

12 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Participants will be included if: 1. they are between 12 and 18 years of age; 2. they have been exposed to at least one or more traumatic event(s) according to the DSM-5 A criteria after the age of 3 years and dating back at least 1 months (with regard to the ability of patients to remember the event(s) and to the high spontaneous remissions of PTSS in the first month after a traumatic event); 3. they exhibit high severity of DSM-5 PTSS as indicated by a total symptom score of ≥25 assessed with the Child and Adolescent Trauma Screen 2 (CATS-2); 4. a nonoffending adult caregiver is available for the treatment and willing to participate in weekly treatment sessions (the inclusion of a caregiver is integral to the TF-CBT treatment model); 5. they are willing and able to attend weekly treatment sessions; 6. if their living circumstances are safe and stable to minimize the risk of re-traumatization during the project; 7. they and their caregiver have sufficient command of the German language (i.e., to participate in assessment \[read\] and treatment\[converse\]); 8. they and their caregivers possess a smartphone. 9. they and their caregiver provided written informed consent. Participants will not be included if: 1. they exhibit acute suicidal behavior or have suicidal ideations requiring immediate hospitalization; 2. they have a documented developmental disorder (i.e., autism spectrum disorder) or current psychosis based on adolescent- and caregiver-report and clinical assessment; 3. they exhibit severe substance misuse based on clinical assessment; 4. take part in concurrent psychotherapy during TF-CBT; 5. exhibit severe intellectual disability based on clinical assessment.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-traumatic stress symptoms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Children's Hospital Zurich

    RECRUITING

    Zurich, Canton of Zurich, 8008, Switzerland

More trials for these conditions

Other studies related to the condition(s) this trial covers.