New hope for rare blood vessel disease: drug aims to cut steroids and keep patients stable
NCT ID NCT06230354
First seen May 02, 2026 · Last updated May 22, 2026 · Updated 5 times
Summary
This study tests a drug called tezepelumab in 42 adults with EGPA, a rare disease that causes inflammation in blood vessels, often leading to asthma and nerve damage. The goal is to see if the drug can help patients achieve remission (no active disease) while taking very low doses of steroids. Participants receive either tezepelumab or a placebo, and doctors monitor their symptoms and steroid use over 24 weeks.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aberdeen Royal Infirmary - NHS Grampian
Aberdeen, AB25 2ZN, United Kingdom
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Barts Health NHS Trust
London, EC1A 7BE, United Kingdom
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Cambridge University Hospitals NHS Foundation Trust
Cambridge, CB2 0QQ, United Kingdom
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Guy's Hospital - Guy's and St Thomas' NHS Foundation Trust
London, SE1 9RT, United Kingdom
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Imperial College Healthcare NHS Trust
London, W2 1PG, United Kingdom
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Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom
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Liverpool University Hospitals NHS Foundation Trust
Liverpool, L7 8YE, United Kingdom
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Royal Brompton Hospital - Guy's and St Thomas' NHS Foundation Trust
London, SW3 6NP, United Kingdom
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Royal Free London NHS Trust
London, NW3 2QG, United Kingdom
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Royal Infirmary of Edinburgh - NHS Lothian
Edinburgh, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust
Birmingham, B15 2GW, United Kingdom
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University Hospitals of Leicester NHS Trust
Leicester, LE3 9QP, United Kingdom
Conditions
Explore the condition pages connected to this study.