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Can texting a therapist beat weekly video sessions for depression?

NCT ID NCT04513080

Symptom relief Sponsor: Talkspace Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether unlimited text-based therapy works as well as weekly video therapy for depression. Over 1,100 adults with depression were randomly assigned to one of the two approaches. Researchers also looked at what treatment options work best for people who don't improve with either method. The goal is to create a flexible, personalized therapy system that adjusts intensity based on patient needs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Message-based psychotherapy and video-chat psychotherapy
What this could lead to
If successful, this could show that text-based therapy is a convenient and effective alternative to weekly video sessions for treating depression.
What could go wrong
This is a completed study, but results may not apply to everyone with depression, and text therapy may not work for severe cases or those with suicidal thoughts.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,184 people

The number who actually took part.

Started

Mar 2020

Finished

Jan 2024

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion and exclusion criteria are the same for Phase 1 and Phase 2. Inclusion Criteria: * 18 years old or older * English or Spanish speaking * Live in the United States * Score of 10 or greater on the Patient Health Questionnaire-9 (PHQ-9) screening * Receive a diagnosis of depression from a Talkspace intake clinician Exclusion Criteria: * Under the age of 18 * Non-English or Spanish speaking * Do not meet criteria for a depressive disorder * Participants with active suicidal ideation or with a primary diagnosis of psychosis will also be excluded and referred to intensive care.

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Conditions

The condition(s) this trial relates to.

depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depressive disorder Study adherence

Contacts and locations

Locations

  • Talkspace

    New York, New York, 10025, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.