Can a common antibiotic ease lingering lyme fatigue?
NCT ID NCT05219929
First seen Jan 11, 2026 · Last updated Jun 12, 2026 · Updated 27 times
Summary
This study tested whether taking tetracycline for 3 months is tolerable for people with Post-Treatment Lyme Disease (PTLD) — those who still have symptoms like fatigue after standard antibiotic treatment. 60 adults received either tetracycline or a placebo, then switched treatments. The main goal was to see how many side effects occurred and if people could stick with the therapy. Results may help decide if larger studies on symptom relief are worthwhile.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Johns Hopkins Lyme Disease Research Center
Lutherville, Maryland, 21093, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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