Can testosterone fix fragile bones in diabetic men?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male veterans only * 35 to 70 years old * With an average fasting morning T level from 2 measurements of \<300 ng/dl taken at least a day apart * symptoms of hypogonadism as assessed using the androgen deficiency in aging male (ADAM) questionnaire * Participants should have * T2D * an A1C of \<11.5 % * a fasting blood sugar of 180 mg/dl * body mass index (BMI) \<40 kg/m2 * with DM of 15 years duration or less to target men who have relatively less complications from long-term DM Exclusion Criteria: * history of prostate or breast cancer * history of testicular disease * untreated severe sleep apnea * ongoing illness that could prevent the subject from completing the study * a hematocrit of \>50% * prostate-related findings as: * a palpable prostate nodule on digital rectal exam (DRE) * serum PSA of 4.0 ng/ml * International Prostate Symptom Score (IPSS) \>19 (severe) * on androgen therapy or selective androgen receptor modulators * on medications that affect bone metabolism such as: * estrogen * selective estrogen receptor modulator as: * raloxifene * aromatase inhibitors * GnRH analogs * glucocorticoids with prednisone equivalent of least 5 mg daily for 1 month * anabolic steroids * phenobarbital and Dilantin * use of bisphosphonates within two years of study entry, i.e.: * risedronate * alendronate * zoledronic acid * pamidronate * diseases that interfere with bone metabolism, as: * hyperparathyroidism * untreated hyperthyroidism * osteomalacia * chronic liver disease * renal failure with estimated glomerular filtration rate of \<45 ml/min * hypercortisolism * malabsorption * immobilization * current alcohol use of \> 3 drinks/day * those with a history of: * deep vein thrombosis * pulmonary embolism * recent stroke or recent diagnosis of coronary artery disease of \< 6 months * because of the potential of being randomized to placebo, subjects with osteoporosis or a BMD T-score by DXA of -2.5 in the lumbar spine, total femur or femoral neck and those with a history of fragility fractures * spine * hip * wrist