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New electric therapy may ease depression without memory loss

NCT ID NCT05172271

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 28 times

Summary

This study tests a new treatment called TEST that uses a weaker electric current than standard electroconvulsive therapy (ECT) for people with depression that hasn't improved with other treatments. The goal is to see if TEST is safe, practical, and can help lift depression while avoiding the memory problems ECT can cause. Eight adults aged 25-64 with major depression or bipolar disorder will receive TEST or a sham (fake) treatment, and their mood and thinking will be tracked for up to 42 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.