Can a tiny electric zing prevent opioid breathing trouble?
NCT ID NCT06823661
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
After surgery, painkillers can slow breathing. This study tested a device that uses a mild electrical pulse on the skin to wake patients when their breathing stops for 10 seconds. Researchers enrolled 60 adults recovering from surgery to see if the system is practical and acceptable. The goal is to make recovery safer without relying on nurses to manually stimulate patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcutaneous electrical nerve stimulation (TENS) device
- What this could lead to
- If this system works, it could offer a simple, automated way to prevent breathing problems after surgery, making recovery safer.
- What could go wrong
- This is a small pilot study testing feasibility, not effectiveness. The device may not reliably detect or correct apnea, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Apr 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Males and females at least 18 years old * Adults undergoing an elective (General, Plastics, Urology, Gynecologic Oncology, Vascular, Otolaryngology, Transplant) surgery with general anesthesia who are recovering in the PACU * American Society of Anesthesiologists (ASA) grade I-IV * Scheduled to be seen at the Pre-Admission Clinic or Surgery Inpatient Unit * Able to complete questionnaires with or without assistance * Able to understand the study protocol, its requirements, risks, and discomforts * Able to provide written informed consent Exclusion Criteria: * A) Preoperative exclusion criteria: * American Society of Anesthesiologists (ASA) grade V-VI * Urgent or emergent surgical procedures that there is insufficient time prior to anticipated commencement of the procedure for participation in the study * Patients with implantable medical electronic devices (eg, pacemaker, implantable cardioverter defibrillator, catheter, and so on.) * Patients with febrile illnesses or acute infectious diseases * Pregnancy * Epilepsy. * B) Postoperative exclusion criteria: * Surgery that would preclude the use of a nasal cannula or face mask used for capnography monitoring (e.g., facial reconstruction) * Postoperative mental status precludes application of study equipment, including a nasal cannula/face mask and/or the stimulation pads (e.g., delirium or agitation during recovering from anesthesia, repeated removal of cannula) * Postoperative admission to the ICU or any site other than the PACU * Need for postoperative assisted ventilation via an endotracheal tube or tracheostomy * An abnormal respiratory tract identified during or immediately after surgery can lead to severe respiratory obstruction * Patients with cardiac arrhythmia (history of atrial fibrillation or bundle branch block) * Skin conditions such as open sores preventing proper application of electrodes * Presence of metal implants in both arms * Lack of access to upper extremities following surgery for application of the stimulation pads
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Toronto General Hospital
Toronto, Ontario, M4Y 1R6, Canada
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Toronto General Hospital
Toronto, Canada
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Other studies related to the condition(s) this trial covers.
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