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Electric brain stimulation shows promise for stroke recovery

NCT ID NCT06134921

Symptom relief Sponsor: Mahidol University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a gentle electrical current applied to the scalp (tES) can improve movement and thinking in people who had a stroke. Sixty adults who had a stroke between 2 weeks and 2 years ago received real or fake stimulation while doing physical therapy. Researchers measured changes in brain activity and motor skills to see if the stimulation helps recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) device
What this could lead to
If it works, this could point toward a safe, non-drug way to boost motor and cognitive recovery after a stroke.
What could go wrong
This is a small, completed study without a treatment phase, so results may not apply widely. The stimulation may cause discomfort or not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Nov 2023

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Stroke individuals aged 18 - 80 years. 2. A first-ever unilateral ischemic or hemorrhagic stroke. 3. Stroke onset from at least 2 weeks - 2 years. 4. Having modified Rankin scale (mRS) 1-4 5. Ability to communicate, follow, and understand the instruction. Exclusion Criteria: 1. Presence of any neurological antecedent, unstable medical conditions or condition that may increase risk of stimulation such as epilepsy and seizure, and history of brain surgery. 2. Presence of metal implantation, intracranial shunt, cochlear implantation, or cardiac pacemakers. 3. Presence of opened wound or infectious wound around the scalp. 4. Moderate pain in any joint of the upper or lower paretic limb (numerical pain rating score \> 4/10). 5. History of receiving non-invasive brain stimulation within the past 6 months.

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Conditions

The condition(s) this trial relates to.

hemorrhagic stroke ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic stroke Hemorrhagic stroke Ischemic stroke Subacute stroke

Contacts and locations

Locations

  • Faculty of Physical Therapy, Mahidol University

    Salaya, Nakonpathom, 73170, Thailand

More trials for these conditions

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