Teprotumumab shows promise in small chinese thyroid eye study
NCT ID NCT07085117
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study looked at how well teprotumumab (TEPEZZA) works in real-world use for 5 Chinese patients with thyroid eye disease. The main goal was to see how many patients had a reduction in eye bulging (proptosis) after their last IV infusion. The study also collected basic information about the patients and their health at the start of treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- teprotumumab (TEPEZZA)
- What this could lead to
- If successful, this could confirm that teprotumumab works in Chinese patients with thyroid eye disease, supporting its use in broader populations.
- What could go wrong
- This is a very small study (only 5 patients) and retrospective, so results may not apply to everyone. No new safety data beyond what is already known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
5 people
The number who actually took part.
- Started
-
Jul 2025
- Finished
-
Aug 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants with TED that have received teprotumumab treatment in BOAO Pilot Zone.
- Ages
-
18 to 120 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Receipt of at least 1 infusion of teprotumumab for treatment of the TED. * Obtained study specific informed consent form (ICF), if required. Exclusion Criteria: * Documentation of non-Chinese ethnicity.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Boao Vanguard Hospital
Qionghai, Hainan, 571400, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a pill tame thyroid eye disease?
- Can a targeted antibody calm thyroid eye disease?
- Could a cholesterol drug shrink eye muscle swelling in thyroid eye disease?
- Can an experimental drug reduce eye bulging in thyroid eye disease?
- Can a new drug ease bulging eyes in thyroid disease?
- New drug IBI3031 enters first human trial for thyroid eye disease