Can a gentle electric current ease the pain of braces?
NCT ID NCT07760337
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This trial tests whether transcutaneous electrical nerve stimulation (TENS) can reduce pain during the initial stage of orthodontic treatment. Using a split-mouth design, each participant receives active TENS on one side of the mouth and a placebo on the other, allowing direct comparison. The goal is to see if this non-invasive, drug-free method can offer a safe alternative to pain medication for people undergoing orthodontic alignment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Transcutaneous electrical nerve stimulation (TENS) device
- What this could lead to
- If effective, TENS could offer a drug-free way to manage pain during orthodontic treatment, improving comfort and compliance.
- What could go wrong
- This is a small early-stage trial, and results may not apply to everyone. TENS may not reduce pain significantly, and it is not suitable for people with certain conditions like epilepsy or pacemakers.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
40 people
The number who actually took part.
- Started
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Mar 2024
- Finished
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Dec 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 57 years
- Sex
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Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: - both male and female patients Age 18-57 years Good oral hygiene Patients in alignment and levelling stage Patients how have not taken any pain medication in the past 24 hours Exclusion Criteria:- Patients with history of epilepsy Patients with cardia arrhythmias and pacemaker Pregnant patients
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Foundation University Islamabad
Islamabad, Federal, 44000, Pakistan
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