Shock therapy for pelvic pain? TENS device trial targets endometriosis
NCT ID NCT07393295
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a small electrical device (TENS) can reduce pelvic pain in women with endometriosis or adenomyosis. 92 women on stable hormone therapy will use the device for 45 minutes daily over 4 weeks, rating their pain on a scale. The goal is to see if the device lowers average pain scores compared to a sham treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- TENS device (transcutaneous electrical nerve stimulation)
- What this could lead to
- If it works, this could offer a drug-free option to manage endometriosis pain at home.
- What could go wrong
- This is a small, early-stage trial with no blinding for the device. Pain is subjective, and results may not apply to all women with endometriosis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 92 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Women aged ≥ 18 years 2. Endometriosis and/or adenomyosis diagnosed by imaging and/or histology 3. Undergoing continuous, stable, and functional hormone treatment (with no menstruation) for at least 2 months 4. No change in hormone treatment planned for the duration of the study 5. Chronic pelvic pain for more than 6 months 6. Pelvic pain at least equal to 2 out of 3 (on the intensity scale: "0 - None," "1 - Mild," "2 - Moderate," "3 - Severe") 7. Agreeing to participate in the study 8. Agrees to limit pain relief treatment during the study to level I painkillers paracetamol and Acupan® (nefopam), and the NSAID Antadys® (flurbiprofen) 9. Has a computer, tablet, or cell phone with an internet connection 10. Is affiliated with a social security system or is a beneficiary of such a system Exclusion Criteria: 1. Pregnant or breastfeeding women 2. Menopausal women 3. Patients who, in the investigator's opinion, have experienced an acute worsening of endometriosis symptoms in the last 28 days 4. Patients with altered sensitivity in the area where the device is applied (hypoesthesia) 5. Skin allergy to the gel or electrodes 6. Dermatological problem in the stimulation area 7. Patients with an implanted pacemaker or active implanted medical device. 8. Epilepsy 9. Current thrombophlebitis or arterial thrombosis 10. Cancer or malignant disease with an expected survival of \< 12 months 11. Alcoholism or drug addiction 12. Fibromyalgia 13. Women who have already tried TENS 14. Patients unable to understand and use the English language to communicate fluently 15. Patients with cognitive impairments 16. Untreated severe psychiatric illness and/or psychological condition that is the primary determinant of the patient's condition 17. Participation in another intervention study that may impact the results of the current study 18. Patient using \> 90 morphine equivalents/day (at least once in the last 28 days) 19. Gynecological and/or endometriosis surgery planned within the next 3 months 20. History of endometriosis surgery within the last 6 months 21. Patient who has undergone a hysterectomy or bilateral oophorectomy 22. Patient under legal protection (guardianship or conservatorship) or patient deprived of liberty
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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IFEM Endo, Clinique Tivoli-Ducos
RECRUITINGBordeaux, 33000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Pre-Surgery pelvic floor therapy stop endometriosis pain after the operation?
- Appendix: the hidden driver of endometriosis pain?
- Allergy pill put to the test against endometriosis pain
- Can ultrasound and tissue clues reveal which endometriosis lesions carry cancer risk?
- Can AI personalize exercise to ease pelvic pain?
- Can AI learn to spot endometriosis and fibroids on ultrasound?