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New drug tested for kids with painful constipation

NCT ID NCT05905926

ENROLLING_BY_INVITATION Symptom relief Sponsor: Ardelyx Source: ClinicalTrials.gov ↗

First seen Jan 12, 2026 · Last updated May 19, 2026 · Updated 23 times

Summary

This study looks at the long-term safety of tenapanor, a drug for irritable bowel syndrome with constipation (IBS-C), in children aged 6 to 17. About 150 kids who completed a prior study will take the drug and be monitored for side effects and heart health. The goal is to see if tenapanor is safe for ongoing use in this age group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AIM Trials, LLC

    Plano, Texas, 75093, United States

  • Advance Clinical Trial PLLC

    Abilene, Texas, 79606, United States

  • Advanced Research Center, Inc.

    Anaheim, California, 92805, United States

  • Advantage Clinical Trials

    The Bronx, New York, 10467, United States

  • Atrium Health

    Charlotte, North Carolina, 28203, United States

  • Boys Town National Research Hospital

    Boys Town, Nebraska, 68010, United States

  • Duke University School of Medicine

    Durham, North Carolina, 27705, United States

  • Florida Pharmaceutical Research and Associates, Inc.

    South Miami, Florida, 33143, United States

  • Frontier Clinical Research

    Kingwood, West Virginia, 26537, United States

  • Frontier Clinical Research, LLC

    Scottdale, Pennsylvania, 15683, United States

  • Frontier Clinical Research, LLC

    Smithfield, Pennsylvania, 15478, United States

  • G & L Research, LLC

    Foley, Alabama, 36535, United States

  • I.H.S. Health, LLC

    Kissimmee, Florida, 34741, United States

  • Maine Health

    Portland, Maine, 04102, United States

  • Mankato Clinic/ Javara Research Ltd

    Mankato, Minnesota, 56001, United States

  • Maspons Pediatric Gastro

    El Paso, Texas, 79902, United States

  • OSF Saint Francis Medical Center

    Peoria, Illinois, 61637, United States

  • Orlando Health, Inc.- APH Center for Digestive Health and Nutrition

    Orlando, Florida, 32806, United States

  • Pioneer Research Solutions Inc

    Sugar Land, Texas, 77479, United States

  • Prisma Health Children's Hospital

    Greenville, South Carolina, 29615, United States

  • Prohealth Research Center

    Doral, Florida, 33166, United States

  • Riley Children's Health

    Indianapolis, Indiana, 46202, United States

  • SUNY Downstate Medical Center

    Brooklyn, New York, 11203, United States

  • Sun Research Institute

    San Antonio, Texas, 78215, United States

  • Texas Digestive Specialists

    Harlingen, Texas, 78550, United States

  • Valencia Medical and Research Center

    Miami, Florida, 33165, United States

Conditions

Explore the condition pages connected to this study.