New hope for kids with IBS-C: Long-Term safety trial of tenapanor begins

NCT ID NCT05905926

ENROLLING_BY_INVITATION Symptom relief Sponsor: Ardelyx Source: ClinicalTrials.gov ↗

First seen Jan 12, 2026 · Last updated May 16, 2026 · Updated 22 times

Summary

This study looks at the long-term safety of tenapanor, a drug that helps with constipation and stomach pain in children aged 6 to 17 with irritable bowel syndrome with constipation (IBS-C). About 150 kids who finished a previous tenapanor study will take the drug for up to a year. The main goal is to check for side effects and monitor heart health.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for IRRITABLE BOWEL SYNDROME WITH CONSTIPATION (IBS-C) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • AIM Trials, LLC

    Plano, Texas, 75093, United States

  • Advance Clinical Trial PLLC

    Abilene, Texas, 79606, United States

  • Advanced Research Center, Inc.

    Anaheim, California, 92805, United States

  • Advantage Clinical Trials

    The Bronx, New York, 10467, United States

  • Atrium Health

    Charlotte, North Carolina, 28203, United States

  • Boys Town National Research Hospital

    Boys Town, Nebraska, 68010, United States

  • Duke University School of Medicine

    Durham, North Carolina, 27705, United States

  • Florida Pharmaceutical Research and Associates, Inc.

    South Miami, Florida, 33143, United States

  • Frontier Clinical Research

    Kingwood, West Virginia, 26537, United States

  • Frontier Clinical Research, LLC

    Scottdale, Pennsylvania, 15683, United States

  • Frontier Clinical Research, LLC

    Smithfield, Pennsylvania, 15478, United States

  • G & L Research, LLC

    Foley, Alabama, 36535, United States

  • I.H.S. Health, LLC

    Kissimmee, Florida, 34741, United States

  • Maine Health

    Portland, Maine, 04102, United States

  • Mankato Clinic/ Javara Research Ltd

    Mankato, Minnesota, 56001, United States

  • Maspons Pediatric Gastro

    El Paso, Texas, 79902, United States

  • OSF Saint Francis Medical Center

    Peoria, Illinois, 61637, United States

  • Orlando Health, Inc.- APH Center for Digestive Health and Nutrition

    Orlando, Florida, 32806, United States

  • Pioneer Research Solutions Inc

    Sugar Land, Texas, 77479, United States

  • Prisma Health Children's Hospital

    Greenville, South Carolina, 29615, United States

  • Prohealth Research Center

    Doral, Florida, 33166, United States

  • Riley Children's Health

    Indianapolis, Indiana, 46202, United States

  • SUNY Downstate Medical Center

    Brooklyn, New York, 11203, United States

  • Sun Research Institute

    San Antonio, Texas, 78215, United States

  • Texas Digestive Specialists

    Harlingen, Texas, 78550, United States

  • Valencia Medical and Research Center

    Miami, Florida, 33165, United States

Conditions

Explore the condition pages connected to this study.