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Zapping the brain without breaking the skin: new study explores Non-Invasive deep stimulation

NCT ID NCT07339072

Knowledge-focused Sponsor: Indiana University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new method called temporal interference (TI) that uses electrical currents to stimulate deep brain areas without surgery. Thirty healthy adults aged 18-50 will receive TI stimulation while their brain activity is measured with fMRI. The goal is to understand how deep brain regions control thinking and behavior, which could lead to future treatments for conditions like addiction, OCD, and Parkinson's disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Between the ages of 18 and 50 * Must have at least a 6th grade education * Ability to speak and read English for all phases Exclusion Criteria: * Currently taking psychotropic medications for ADHD, other mental illness, or medications for cancer * History of epilepsy or seizure disorders * History of migraines or other neurological syndromes * History of AIDS (due to potential cognitive deficits) * History of head trauma or cognitive impairments * Personal experiences consistent with symptoms of psychosis (e.g., hallucinations, delusions of control or special powers) * History of skull defects (e.g., holes bored into the skull or known cranial fissures) * Metal implants in the head or under the scalp * Does not meet fMRI safety screening criteria (e.g., metal implants in the body, permanent jewelry, tattoos on the head or neck) * Uses an intrauterine device (IUD) for birth control and cannot provide documentation to verify MRI safety * Pregnancy (self-reported; no pregnancy test administered) * Weight over 440 lbs (scanner weight limit) * Presence of pacemakers

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Indiana University Bloomington, Imaging Research Facility

    RECRUITING

    Bloomington, Indiana, 47408, United States

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