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Remote workouts may rewire brains after stroke

NCT ID NCT06525987

Symptom relief Sponsor: University of L'Aquila Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 24-week home exercise program, guided by a coach over video calls, can improve brain connections and physical fitness in people aged 60 and older who have had a lacunar stroke. Sixty participants will be split into two groups: one starts exercise right away, the other waits. Researchers will measure changes in brain activity and fitness levels to see if remote coaching helps recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥60 years; * History of lacunar stroke occurred between 3 months and 10 years from screening and confirmed by neuroimaging or clinical data by an expert stroke physician; * Modified Rankin Scale (mRS) score of 0-1, indicating no symptoms or no significant disability; * A level of physical activity below recommended targets, i.e. \<150 minutes per week of moderate-to-vigorous exercise (24); * Ability to sign informed consent. Exclusion Criteria: * Uncontrolled hypertension; * Heart disease impairing the possibility of safely following an exercise protocol at the discretion of the treating physician; * Primary or secondary epilepsy; * Prostheses, implants, and any device that might impair the performance of either high-density electroencephalogram or the exercise intervention; * Cognitive impairment (Mini Mental State Examination score ≤26 at follow-up); * Lack of access to Internet-based facilities or poor technological alphabetization impairing the adherence to the trial protocol; * Any major physical or psychiatric comorbidity that in the judgement of the treating physician might compromise the ability to undergo an exercise intervention.

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Conditions

The condition(s) this trial relates to.

Cerebral Small Vessel Diseases cerebrovascular disorder Stroke, Lacunar

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lacunar stroke Small vessel cerebrovascular disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UOC Neurologia e Stroke Unit

    RECRUITING

    Avezzano, L'Aquila, 67051, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.