New hope against stomach bug in Antibiotic-Resistant region
NCT ID NCT06382493
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two treatments for H. pylori infection, a common stomach bug. One uses a newer drug called tegoprazan, while the other uses a standard proton pump inhibitor. The trial will enroll 400 adults in South Korea, where antibiotic resistance makes treatment difficult. The goal is to see which approach clears the infection more effectively.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Tegoprazan
- What this could lead to
- If successful, this could offer a more effective treatment option for H. pylori infection in regions with high antibiotic resistance.
- What could go wrong
- This is a single-center trial with 400 participants, so results may not apply broadly. The study is early and does not yet prove long-term benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients who had H. pylori infection proved by positive test result of urea breath test (UBT), rapid urase test or pathologic examination (warthin-giemsa staining) Exclusion Criteria: * congestive heart failure, NYHA III or IV * end-stage renal disease * alcoholics * drug abusers * pregnant or nursing women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Seoul National University Bundang Hospital
RECRUITINGSeongnam-si, Gyeonggi-do, 463-707, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can probiotics make h. pylori antibiotics easier on the gut?
- Can a common seed oil boost stomach infection treatment?
- Two antibiotic cocktails face off to wipe out stomach bacteria
- Could a routine blood count reveal hidden stomach infection?
- A simple breath test after a heart attack could prevent dangerous bleeding