Can your phone replace a doctor visit for MS relapses?
NCT ID NCT02454907
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether smartphone communication and a special questionnaire could help confirm MS relapses without requiring an in-person visit. Researchers worked with 150 people with relapsing-remitting MS to see if this approach improves patient satisfaction and care. The goal was to make it easier for patients to get timely help when symptoms flare up.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to easier ways for MS patients to confirm relapses without always needing an in-person doctor visit.
- What could go wrong
- This is a small, completed study focused on testing a questionnaire and communication method, not a treatment. Results may not apply to all MS patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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150 people
The number who actually took part.
- Started
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Jul 2018
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * English speakers * Relapsing-remitting MS (2010 criteria) * Expanded Disability Status Scale (EDSS) ≤6.0 * Possession of a smartphone OR of a mobile telephone with text messaging AND an e-mail account AND web access OR willingness to be provided with, and utilize, a smartphone for the duration of the study * In the two years before screening: at least two relapses, OR one relapse and two new lesions (unrelated to relapse symptoms) on magnetic resonance imaging (MRI), OR RRMS (MAGNIMS 2010 criteria) onset within the past year with no exposure to disease modifying therapies (DMT) * Patient is starting one of the following MS therapies: injectable (subcutaneous interferon beta or glatiramer acetate) or oral (fingolimod, teriflunomide, or dimethyl fumarate) therapies * Relapse and MRI activity occurred while untreated or despite one single treatment, and no change in therapy since that activity * Lives within 100 miles of Johns Hopkins Medical Center (Baltimore, MD) Exclusion Criteria: * History of DMT exposure if MAGNIMS 2010 criteria used to enroll patients with disease onset in the past year, or change in MS therapy since qualifying relapse/MRI criteria occurred
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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