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Could a simple mist replace surgery for bleeding tonsils?

NCT ID NCT06580509

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 32 times

Summary

After a child's tonsils are removed, bleeding can sometimes occur and may require another surgery. This pilot study tests whether a nebulized mist of the drug tranexamic acid (TXA) can stop the bleeding without needing to touch the sore area. Twelve children aged 2 to 17 who come to the emergency room with post-tonsillectomy bleeding will receive either TXA mist or a placebo. The study focuses on whether the treatment is feasible and how the drug is absorbed, not yet on proving it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tranexamic acid (TXA) given as a mist to inhale

What this could lead to

If it works, this could offer a non-surgical way to stop bleeding after tonsil removal in children, reducing the need for repeat surgery or blood transfusions.

What could go wrong

This is a very early pilot study with only 12 children, so it is too small to prove effectiveness. The mist may not deliver enough medicine to the bleeding site, and side effects are not yet well understood.

Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.