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Shocking the brain back to reading: new hope for aphasia

NCT ID NCT06891638

Symptom relief Sponsor: Kessler Foundation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) and Phono-Motor Treatment (PMT)
What this could lead to
If it works, this could point toward a more effective reading therapy for people with aphasia after stroke.
What could go wrong
This was a very small, early study with only 6 participants, so results may not apply to everyone. The approach is still experimental.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

6 people

The number who actually took part.

Started

May 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Chronic (\>6 months) left-hemisphere stroke * Aphasia diagnosis. * Deficits in reading aloud. Exclusion Criteria: * Eye condition not correctable with lenses and interfering with reading (e.g., blindness) * Severe apraxia of speech or cognitive deficits preventing participation. * Participation in one-on-one aphasia rehabilitation during the study period. * Brain disorders other than stroke (such as Alzheimer's Disease or Dementia, Parkinson's Disease, etc) * Contraindications of tDCS or MRI * Skin condition affecting the scull (e.g., psoriasis) or open wounds at the stimulation site. * Presence of metallic implants (e.g., cardiac stimulators or pacemakers, cochlear implants) * History of ongoing/unmanaged seizers * Pregnancy * Claustrophobia * Inability to lie flat on the back

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Conditions

The condition(s) this trial relates to.

aphasia communication disorder dyslexia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aphasia Stroke

Contacts and locations

Locations

  • Kessler Foundation

    West Orange, New Jersey, 07052, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

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