Shock and serenity: new combo tackles Post-Surgery pain
NCT ID NCT05673720
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether combining a gentle brain stimulation technique (transcranial direct current stimulation) with mindfulness exercises could reduce pain after knee replacement surgery. Twenty-four adults who had knee replacement took part. The goal was to see if this approach is practical and acceptable, and to get early data on whether it might lower pain and the need for painkillers.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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24 people
The number who actually took part.
- Started
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May 2023
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * elective unilateral knee total replacement * mentally capable of reading, giving consent and following instructions * being able to answer questions in English * not pregnant Exclusion Criteria: * history of brain surgery, brain tumor, seizure, stroke, or intracranial metal implantation * systemic rheumatic disorders, including rheumatoid arthritis, systemic lupus erythematosus, and fibromyalgia * alcohol/substance abuse * current use of sodium channel blockers, calcium channel blockers and NMDS receptor antagonists * hospitalization within the preceding year for psychiatric illness * no access to a device with internet access that can be used for secure videoconferencing for real-time remote supervision
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tallahassee Orthopedic Clinic
Tallahassee, Florida, 32308, United States
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Other studies related to the condition(s) this trial covers.
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