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Zapping the brain to restore swallowing after stroke

NCT ID NCT07732673

Disease control Sponsor: Juliane Lisboa Pereira Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial tests whether a gentle electrical current applied to the brain — called transcranial direct current stimulation (tDCS) — can help older adults recover the ability to swallow after a stroke. Hospitalized patients aged 60 to 80 with swallowing difficulties will receive either real or sham tDCS alongside standard speech therapy for 10 sessions. The goal is to see if adding brain stimulation speeds up recovery compared to therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) — a non-invasive brain stimulation device
What this could lead to
If it works, this could offer a safe, drug-free way to speed up swallowing recovery after a stroke, reducing complications like pneumonia.
What could go wrong
This is a small, early-stage trial with 66 participants. tDCS may cause mild scalp discomfort, and the added benefit over standard therapy alone is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Inpatients at Hospital Regional Dr. Abelardo Santos. Aged 60 to 80 years. Diagnosis of neurogenic oropharyngeal dysphagia ranging from mild-to-moderate, moderate, to moderate-to-severe (Padovani et al., 2007). Ischemic or hemorrhagic stroke with unilateral cortical lesion, confirmed by brain imaging (Computed Tomography or Magnetic Resonance Imaging). Subacute phase of stroke (from day 8 post-ictus up to 6 months after stroke onset). Hemodynamically stable. Glasgow Coma Scale score of 13, enabling participation in the intervention protocol. Signed Informed Consent Form provided by the participant or their legally authorized representative. Exclusion Criteria: Patients who underwent surgical intervention due to stroke. Presence of electronic devices or metallic implants in the skull or cervical region. History of recent seizures or uncontrolled epilepsy. Presence of other neurological diseases associated with stroke (e.g., Alzheimer's disease, Parkinson's disease). History of multiple previous strokes. Dysphagia resulting from other etiologies, such as cervical trauma or head and neck neoplasms. Cognitive impairment preventing proper participation in the proposed intervention protocol. Occurrence of any allergic reaction or adverse effect related to transcranial direct current stimulation (tDCS).

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Conditions

The condition(s) this trial relates to.

Deglutition Disorders stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dysphagia Stroke

Contacts and locations

Locations

  • Hospital Regional Dr Abelardo Santos

    Belém, Pará, 66811-000., Brazil

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Other studies related to the condition(s) this trial covers.