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Zapping the brain to beat Post-Stroke fatigue and boost speech

NCT ID NCT07151677

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a gentle electrical current applied to the front of the brain (tDCS) can reduce fatigue and improve language and attention in people who have had a stroke. Sixty participants will receive either real or fake tDCS during 10 sessions of speech therapy. The goal is to see if the real stimulation leads to better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) device
What this could lead to
If it works, this could offer a new way to ease post-stroke fatigue and improve language and attention without medication.
What could go wrong
This is an early-stage study with only 60 participants, so results may not apply to everyone. The effect of tDCS is still uncertain, and some people may not benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Nov 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. 18 years or older. 2. No diagnosis of neurological disorder (other than stroke). 3. No diagnosis of psychiatric disorder, with the exception of anxiety and/or depression if it is managed through medication and/or behavioral intervention. 4. No seizure within the past 6 months. 5. Not pregnant. 6. Does not currently have cardiac pacemaker 7. In chronic phase of recovery, defined as at least 6 months post-stroke. 8. Not undergoing speech and language therapy targeting auditory comprehension or attention for the duration of the study. 9. No metal implants in the scalp or bone in the pre-frontal area of the head. 10. No unhealed skull fractures. 11. Onset of aphasia related to single, left hemisphere, ischemic stroke. 12. Damaged brain tissue from stroke does not overlap with left hemisphere dorsolateral prefrontal cortex. 13. Mild to moderate aphasia (as measured by WAB-R \*\*or QAB). 14. Self-report of post-stroke fatigue (as measured on SF-CAT) 15. No significant challenges with vision or hearing (with use of corrective aids if needed; eyeglasses, hearing aids). 16. Willing to allow audio-recording of study sessions. Exclusion Criteria: 1. Younger than 18 years old. 2. Diagnosis or history of neurological disorder other than stroke. 3. Diagnosis or history of psychiatric disorder with the exception of anxiety and/or depression if it is managed through medication and/or behavioral intervention. 4. History of seizures within the past 6 months. 5. Pregnant. 6. Currently has cardiac pacemaker 7. \<6 months post-stroke (however, if this is only exclusionary criterion met, participant can be re-evaluated at the 6-month mark if still interested in the study) 8. Currently undergoing speech and language therapy targeting auditory comprehension or attention. 9. Metal implants in the scalp or bone in the pre-frontal area of the head. 10. Currently has an unhealed skull fracture. 11. Onset of aphasia related to etiology other than ischemic left hemisphere stroke. 12. Damaged brain tissue significantly overlaps with left hemisphere dorsolateral prefrontal cortex. 13. No aphasia or severe aphasia (as measured by WAB-R \*\*or QAB). 14. Does not report experience of post-stroke fatigue (as measured on SF-CAT) 15. Significant challenges with vision and/or hearing (even with use of corrective aids). 16. Unwilling to allow audio-recording of study sessions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Syracuse University

    RECRUITING

    Syracuse, New York, 13244, United States

  • University of Michigan

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

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