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Brain zaps for breathlessness: tiny trial tests tDCS in COPD Flare-Ups

NCT ID NCT06944626

Symptom relief Sponsor: Okan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This small study tested whether a painless brain stimulation technique called tDCS could reduce shortness of breath in people hospitalized with a COPD flare-up. Thirty participants received either real tDCS or a sham version, plus standard physiotherapy, over three days. Researchers measured breathing, lung function, and daily activity levels to see if the brain stimulation made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could offer a new, non-drug way to help COPD patients feel less breathless during a flare-up.
What could go wrong
This is a very small, early study with only 30 people. The results may not apply to everyone, and the effect might be small or not last long.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Apr 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with COPD and followed up for at least 6 months * Hospitalised due to an exacerbation * Have not taken any medication affecting the nervous system in the last 6 months * Co-operative * Have the ability to participate in working procedures * Over 18 years of age, * The specialist physician finds it suitable for physiotherapy applications, * Volunteers who want to participate in the study Exclusion Criteria: * Having comorbidities other than COPD, such as bronchiectasis, lung cancer or asthma * Surgery in the last 6 months (volume reduction surgery, etc.) * Neuromuscular disease * Pulmonary embolism or pulmonary oedema * Presence of cranial, cardiac, spinal cord, intra-aural metal implants * Epilepsy * Patients on invasive mechanical ventilation * Patient with cardiac pace maker

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD Dyspnea TDCS

Contacts and locations

Locations

  • İstinye Üniversitesi

    Istanbul, Zeytinburnu, 08100, Turkey (Türkiye)

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