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Zapping the brain to help stroke survivors speak again

NCT ID NCT04963803

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a gentle, non-invasive brain stimulation called tDCS could make speech therapy work better for people with aphasia (trouble speaking or understanding language) after a stroke. 23 adults who were at least 6 months past their stroke received speech therapy along with either real or fake tDCS. The goal was to see if the real stimulation improved language comprehension more than the fake one.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

23 people

The number who actually took part.

Started

Jul 2021

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. 18 years or older. 2. No diagnosis of neurological disorder (other than stroke). 3. No diagnosis of psychiatric disorder. 4. No seizure within the past 6 months. 5. Not pregnant. 6. In chronic phase of recovery, defined as at least 6 months post-stroke. 7. Not undergoing speech and language therapy targeting auditory comprehension or attention for the duration of the study. 8. No metal implants in the head. 9. No unhealed skull fractures. 10. Onset of aphasia related to left hemisphere stroke. 11. Damaged brain tissue from stroke does not overlap with left hemisphere dorsolateral prefrontal cortex. 12. Mild to moderate aphasia. 13. Cognitive ability minimally within functional limits. 14. Able to pass vision and hearing screening (with use of corrective aids if needed; eyeglasses, hearing aids). 15. Willing to allow audio-recording of study sessions. Exclusion Criteria: 1. Younger than 18 years old. 2. Diagnosis or history of neurological disorder other than stroke. 3. Diagnosis or history of psychiatric disorder. 4. History of seizures within the past 6 months. 5. Pregnant. 6. \<6 months post-stroke (however, if this is only exclusionary criterion met, participant can be re-evaluated at the 6-month mark if still interested in the study) 7. Currently undergoing speech and language therapy targeting auditory comprehension or attention. 8. Metal implants in the head. 9. Currently has a skull fracture. 10. Onset of aphasia related to etiology other than left hemisphere stroke. 11. Damaged brain tissue includes left hemisphere dorsolateral prefrontal cortex. 12. No aphasia or severe aphasia. 13. Cognitive ability below functional limits. 14. Unable to pass vision and/or hearing screening with use of corrective aids. 15. Unwilling to allow audio-recording of study sessions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Syracuse University

    Syracuse, New York, 13244, United States

More trials for these conditions

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