Brain stimulation trial aims to rewire fear responses in anxiety
NCT ID NCT07405463
First seen Feb 12, 2026 · Last updated Jun 22, 2026 · Updated 24 times
Summary
This study tests whether a single session of transcranial direct current stimulation (tDCS) can improve the brain's ability to update fear and safety associations in people with anxiety disorders. 140 participants will be randomly assigned to receive either active stimulation targeting specific brain regions or a sham (placebo) stimulation. The main goal is to see if tDCS boosts cognitive flexibility during a fear reversal task.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Shenzhen Kangning Hospital
Guangzhou, Guangdong, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could point toward a non-drug brain stimulation technique to help people with anxiety disorders better unlearn fears.
What could go wrong
This is a small, early-stage study with only a single session of stimulation. It may not produce lasting or clinically meaningful changes, and results may not apply to all anxiety disorders.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.