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Shock therapy for arthritis? mild zaps aim to calm Kids' joint pain

NCT ID NCT05710640

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 22 times

Summary

This study tested a device that sends mild electrical pulses through the skin to stimulate the vagus nerve, aiming to reduce pain and inflammation in children with juvenile idiopathic arthritis (JIA). The trial enrolled 18 participants aged 5-18 and compared active stimulation to a sham (fake) treatment. The study was terminated early, so results are limited, but the approach was considered safe and aimed at easing symptoms rather than curing the disease.

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Contacts and locations

Locations

  • Division of Pediatric Rheumatology at the University of Utah School of Medicine and Primary Children's Hospital

    Salt Lake City, Utah, 84132, United States

  • Feinstein Institutes for Medical Research, Cohen Children's Medical Center: Pediatric Rheumatology

    Lake Success, New York, 11040, United States

  • Indiana University Medical Center: Riley Hospital for Children Department of Pediatric Rheumatology

    Indianapolis, Indiana, 46202, United States

  • Nemours Children's Health: Department of Pediatric Rheumatology

    Orlando, Florida, 32827, United States

  • Seattle Children's Hospital: Rheumatology Clinic

    Seattle, Washington, 98105, United States

  • Stephen D. Hassenfield Children's Center at NYU Langone Health

    New York, New York, 10016, United States

  • University of California San Francisco School of Medicine: Department of Pediatrics, Division of Pediatric Rheumatology

    San Francisco, California, 94158, United States

Conditions

Explore the condition pages connected to this study.