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New TB vaccine trial aims to stop infection before it starts

NCT ID NCT06050356

First seen Jan 31, 2026 · Last updated May 23, 2026 · Updated 14 times

Summary

This study tests a new vaccine called H107e/CAF®10b to prevent tuberculosis (TB). It is the first time this vaccine is given to people, so the main goal is to check its safety and how well it triggers the immune system. The trial involves 140 healthy adults aged 18 to 45. The vaccine uses protein pieces from the TB bacteria plus an adjuvant to boost the body's defense, aiming to create immune memory that can fight off future TB infection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aurum Institute

    Pretoria, Gauteng, 0028, South Africa

Conditions

Explore the condition pages connected to this study.