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Heatwave hope: taurine and beetroot may boost sweating in diabetes patients

NCT ID NCT07656051

Symptom relief Sponsor: University of Portsmouth Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking taurine and beetroot supplements can improve how people with type 2 diabetes regulate their body temperature during extreme heat. Researchers will measure sweating and core temperature in 18 adults during a heat exposure session. The goal is to find a simple, safe way to reduce heat-related health risks in this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
taurine and beetroot (nitrate) supplements
What this could lead to
If it works, this could point toward a simple dietary strategy to help people with type 2 diabetes stay safer during heatwaves.
What could go wrong
This is a very small, early-stage trial (18 people) testing only an acute effect. Results may not apply to everyone or lead to a practical treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 18 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female (post-menopausal) aged 35 years or above. * Diagnosed with T2DM as defined by the WHO (HbA1c ≥48 mmol/mol). * Willing and able to give informed consent for participation in the study. * Able to understand and fully cooperate with the study protocol. Exclusion Criteria: * Severe peripheral neuropathy (to the point to which they cannot sense temperature) * Uncontrolled hypertension (≥180 systolic / 100 diastolic) * Significant renal impairment (eGFR \< 30) * Diagnosed anhidrosis * Taking any medication which may interfere with data interpretation or safety * Who have had a myocardial infarction or cerebrovascular event * Any cardiac abnormalities which restrict hard exercise * Any allergies to the ingredients used in the supplements * BMI \>40 * Current smokers or who have stopped within 3 months * Unable to understand and/or fully cooperate with the study protocol * Any serious medical condition which would interfere with data interpretation or safety will be excluded from participation. * Open wounds * Skin ulcerations (that would interfere with data collection and interpretation or safety) * Eczema (that would interfere with data collection and interpretation or safety) * Pre-existing postural hypertension * Existing cardiac diseases (identified during screening) * Currently heat acclimated (repeated exposure to hot environments ≥3 sessions in the last 14-21 days) * Prior heat related illness

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type 2 diabetes

How to take part

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  1. The official record

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More trials for these conditions

Other studies related to the condition(s) this trial covers.