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Taste and smell changes in chemo: key to better nutrition?

NCT ID NCT06643026

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how chemotherapy affects taste and smell in 69 people with digestive cancers. Researchers used questionnaires to track changes in food preferences and eating habits before, during, and after the first round of chemo. The goal was to understand how these sensory changes might contribute to malnutrition, a common problem in cancer patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better understand why some cancer patients struggle with eating, leading to more personalized nutritional support.
What could go wrong
This is a small, completed observational study with only 69 participants. It does not test a new treatment, so it cannot directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

69 people

The number who actually took part.

Started

Nov 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with malignant digestive tumors receiving active chemotherapy

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to complete the proposed questionnaires * Patients over 18 years of age * Non-opposed patients * Digestive cancers starting chemotherapy and/or immunotherapy * Able to eat by mouth Exclusion Criteria: * Concomitant treatment for a non-digestive cancer (excluding basal/spinocellular carcinoma and chronic haemopathy) * Previous ENT surgery (face/neck) * Exclusive enteral feeding (nasogastric tube, gastrostomy) or parenteral nutrition * Previous chemotherapy/immunotherapy \< 5 years * Individuals deprived of liberty by a judicial or administrative decision

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Croix Rousse

    Lyon, 69004, France

  • Hôpital Edouard Herriot

    Lyon, 69003, France

  • Hôpital Lyon Sud

    Pierre-Bénite, 69495, France

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