Withdrawn study sought to stop brain 'Storms' after blood clot surgery
NCT ID NCT04966546
First seen Feb 19, 2026
Summary
This study planned to test whether the drug memantine could reduce harmful brain waves called spreading depolarizations after surgery for chronic subdural hematoma, a common condition in older adults where fluid compresses the brain. The trial was withdrawn before any participants were enrolled, so no data was collected. The goal was to see if blocking these brain waves could prevent post-surgery confusion or weakness.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
-
University of New Mexico
Albuquerque, New Mexico, 87131, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Memantine Hydrochloride
What this could lead to
If it had worked, this could point toward a treatment to reduce confusion or weakness after brain surgery for chronic subdural hematoma.
What could go wrong
The trial was withdrawn before enrolling anyone, so no results exist. It was a very early feasibility study, and memantine's effect on these brain waves was unproven.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.