New hope for colorectal cancer: drug duo aims to wipe out hidden tumor DNA
NCT ID NCT05343013
First seen Feb 20, 2026 · Last updated Jun 17, 2026 · Updated 19 times
Summary
This study tests whether adding celecoxib to TAS-102 can clear tiny amounts of cancer DNA (ctDNA) in the blood of colorectal cancer patients who have finished standard chemotherapy. About 25 adults with stage II-IV colorectal cancer and no visible tumors on scans will take TAS-102 with or without celecoxib for 6 months. The goal is to see if the combination can eliminate these leftover cancer signals and reduce the risk of the cancer coming back.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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