Nerve block may replace curare in laparoscopic surgery
NCT ID NCT01628952
First seen Nov 19, 2025 · Last updated Jun 22, 2026 · Updated 28 times
Summary
This study compares two ways to relax the abdominal muscles during laparoscopic (keyhole) digestive surgery. One method is a nerve block called TAP block, which numbs the abdominal wall. The other is a standard muscle relaxant drug called curare. The trial involves 60 adults aged 18-75 undergoing laparoscopic surgery. Researchers will measure how well each method relaxes the muscles by checking how much air is needed to inflate the abdomen during surgery.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Sign up to get updates when this study changes or when new studies for THE MAIN OF THIS STUDY IS TO COMPARE THE NERVE BLOCK OF THE MUSCLES OF THE ABDOMINAL WALL BETWEEN THE BILATERAL TAP BLOCK AND CURARE are added.
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Contacts and locations
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Locations
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CHU Amiens
Amiens, Picardie, 80054, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transversus Abdominis Plane (TAP) block (local anesthetic) and curare (muscle relaxant drug)
What this could lead to
If successful, this could show that a nerve block provides adequate muscle relaxation without the side effects of curare, potentially improving recovery after laparoscopic surgery.
What could go wrong
This is a small, single-center Phase 4 trial with only 60 participants. The results may not apply to all patients or surgeries, and the nerve block might not work as well as curare in some cases.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.