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New pill could reduce sleep attacks and muscle weakness in narcolepsy

NCT ID NCT06505031

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 28 times

Summary

This study tested a new drug called TAK-861 in 105 people with narcolepsy type 1, a condition causing severe daytime sleepiness and sudden muscle weakness (cataplexy). The goal was to see if the drug improves alertness and reduces cataplexy attacks after 3 months. Participants took either TAK-861 or a placebo, and researchers measured sleepiness using a wakefulness test and questionnaires.

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Contacts and locations

Locations

  • 28003

    Barcelona, 08035, Spain

  • Takeda Site 1

    Glebe, New South Wales, Australia

  • Takeda Site 10

    Suwon, Gyeonggi-do, 16247, South Korea

  • Takeda Site 11

    Seoul, Daegu, 41931, South Korea

  • Takeda Site 12

    Seoul, 3080, South Korea

  • Takeda Site 13

    Madrid, Spain

  • Takeda Site 14

    Marseille, 13385, France

  • Takeda Site 15

    Nantes, 44093, France

  • Takeda Site 16

    Léon, Bordeaux, 33076, France

  • Takeda Site 17

    Pozzilli, 86077, Italy

  • Takeda Site 19

    Uppsala, Sweden

  • Takeda Site 2

    Alken, Belgium

  • Takeda Site 20

    Helsinki, 380, Finland

  • Takeda Site 21

    Tampere, 33520, Finland

  • Takeda Site 22

    Linz, 4020, Austria

  • Takeda Site 23

    Liège, 4000, Belgium

  • Takeda Site 24

    Leuven, 3000, Belgium

  • Takeda Site 25

    Ghent, 9000, Belgium

  • Takeda Site 26

    Guangdong, China

  • Takeda Site 27

    Zhengzhou, Henan, China

  • Takeda Site 28

    Shanghai, Shanghai Municipality, China

  • Takeda Site 3

    Erpent, 5101, Belgium

  • Takeda Site 4

    Beijing, Beijing Municipality, China

  • Takeda Site 5

    Montpellier, France

  • Takeda Site 6

    Bron, France

  • Takeda Site 7

    Bologna, 40139, Italy

  • Takeda Site 8

    Roma, Italy

  • Takeda Site 9

    Krakow, Poland

Conditions

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