New pill could help narcolepsy patients stay awake and avoid sudden muscle collapse

NCT ID NCT06505031

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 27 times

Summary

This study tested an experimental drug called TAK-861 in 105 people with narcolepsy type 1, a condition that causes severe daytime sleepiness and sudden muscle weakness (cataplexy). The goal was to see if the drug could help people stay awake during the day and reduce the number of cataplexy attacks after 3 months of treatment. The trial compared TAK-861 to a placebo to measure its effectiveness and safety.

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Contacts and locations

Locations

  • 28003

    Barcelona, 08035, Spain

  • Takeda Site 1

    Glebe, New South Wales, Australia

  • Takeda Site 10

    Suwon, Gyeonggi-do, 16247, South Korea

  • Takeda Site 11

    Seoul, Daegu, 41931, South Korea

  • Takeda Site 12

    Seoul, 3080, South Korea

  • Takeda Site 13

    Madrid, Spain

  • Takeda Site 14

    Marseille, 13385, France

  • Takeda Site 15

    Nantes, 44093, France

  • Takeda Site 16

    Léon, Bordeaux, 33076, France

  • Takeda Site 17

    Pozzilli, 86077, Italy

  • Takeda Site 19

    Uppsala, Sweden

  • Takeda Site 2

    Alken, Belgium

  • Takeda Site 20

    Helsinki, 380, Finland

  • Takeda Site 21

    Tampere, 33520, Finland

  • Takeda Site 22

    Linz, 4020, Austria

  • Takeda Site 23

    Liège, 4000, Belgium

  • Takeda Site 24

    Leuven, 3000, Belgium

  • Takeda Site 25

    Ghent, 9000, Belgium

  • Takeda Site 26

    Guangdong, China

  • Takeda Site 27

    Zhengzhou, Henan, China

  • Takeda Site 28

    Shanghai, Shanghai Municipality, China

  • Takeda Site 3

    Erpent, 5101, Belgium

  • Takeda Site 4

    Beijing, Beijing Municipality, China

  • Takeda Site 5

    Montpellier, France

  • Takeda Site 6

    Bron, France

  • Takeda Site 7

    Bologna, 40139, Italy

  • Takeda Site 8

    Roma, Italy

  • Takeda Site 9

    Krakow, Poland

Conditions

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