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Tailored gut bypass could curb obesity and malnutrition risks

NCT ID NCT07289555

Disease control Sponsor: El-Sahel Teaching Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

This study tests a new, personalized version of a weight-loss surgery called SADI-S. Surgeons will measure each patient's small intestine and adjust the bypass length to maximize weight loss while lowering the risk of vitamin deficiencies. The study includes 40 adults with obesity, and participants will be followed for at least a year to track weight, health improvements, and side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-65 years. * BMI ≥35 kg/m² or BMI ≥30 kg/m² with obesity-related comorbidities such as type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, obstructive sleep apnea, or non-alcoholic fatty liver disease. * Willingness to adhere to follow-up visits and testing. * Indicated for revisional SADI-S post sleeve gastrectomy for inadequate weight loss or weight regain. Exclusion Criteria: * Severe uncontrolled medical or psychiatric conditions preventing adherence to the protocol. * Known short bowel syndrome or previous extensive bowel resections or intraoperative finding of extensive bowel adhesions.

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Conditions

The condition(s) this trial relates to.

Malnutrition morbid obesity nutritional deficiency disease obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bariatric surgery Comorbidities Malnutrition Morbid obesity

Contacts and locations

Locations

  • El Sahel Teaching Hospital

    Cairo, Greater Cairo, 11697, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.