Major trial tests cutting unnecessary radiation for Low-Risk breast cancer

NCT ID NCT03488693

Disease control Sponsor: Canadian Cancer Trials Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study is for women with a low-risk type of breast cancer that has spread to nearby lymph nodes or is T3N0. It compares standard care (which includes radiation to the lymph node area) against skipping that extra radiation. The goal is to see if avoiding regional radiation works just as well at keeping the cancer from coming back, while reducing side effects. About 2,140 women will take part in this phase 3 trial.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

2,138 people

The number who actually took part.

Started

Oct 2018

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients must be women with newly diagnosed histologically proven invasive carcinoma of the breast with no evidence of metastases, staged as per site standard of care. * Patients must have been treated by BCS or mastectomy with clear margins of excision. Post-mastectomy positive margins for invasive disease and/or DCIS is not allowed. Multifocal disease (i.e. the presence of two or more foci or breast cancer within the same breast quadrant) and multicentric disease (i.e. the presence of two or more foci of breast cancer in different quadrants of the same breast) are allowed. * Patients with T3N0 disease are eligible. * Patients with disease limited to nodal micrometastases are eligible * Patients with nodal macrometastases (\>2mm) treated by axillary dissection must have 1-3 positive axillary nodes (macrometastases, \> 2 mm). * Patients treated by mastectomy and SLNB alone must have only 1-2 positive axillary nodes (macrometastases, \> 2 mm). * Patients must be ER ≥ 1% and HER2 negative on local testing * Patients must have an Oncotype DX recurrence score ≤25 obtained from testing of breast tumour tissue from a core biopsy or from the surgical specimen. * Patient must consent to provision of, and investigator(s) must agree to submit to the CCTG Central Tumour Bank, a representative formalin fixed paraffin block of tumour tissue in order that the specific correlative marker assays described in the protocol may be conducted * Patient must consent to provision of samples of blood in order that the specific correlative marker assays described in the protocol may be conducted. * Patients must have had endocrine therapy initiated or planned for ≥ 5 years. Premenopausal women will receive ovarian ablation plus aromatase inhibitor therapy or tamoxifen if adjuvant chemotherapy was not administered. For all patients, endocrine therapy can be given concurrently or following RT. * Patients may or may not have had adjuvant chemotherapy. * RT must commence within 16 weeks of definitive surgery if the patient is not treated with chemotherapy. If adjuvant chemotherapy is given, RT must begin within 12 weeks after the last dose. (Note: adjuvant chemotherapy may be ongoing at the time of randomization). Definitive surgery is defined as the last breast cancer-related surgery. * Patient's ECOG performance status must be 0, 1 or 2. * Patient's age must be ≥ 35 years. * For the first 736 eligible English or French-speaking subjects who have agreed to optional questionnaire completion: Patient is able (i.e. sufficiently fluent) and willing to complete the quality of life, health utilities and lost productivity questionnaires in either English or French (note: enrollment completed 2022Aug02) * Patient consent must be appropriately obtained in accordance with applicable local and regulatory requirements * Patients must be accessible for treatment and follow-up. Investigators must assure themselves the patients randomized on this trial will be available for complete documentation of the treatment, adverse events, and follow-up. * In accordance with CCTG policy, protocol treatment is to begin within 6 weeks of patient randomization. * Women of childbearing potential must have agreed to use an effective contraceptive method. A woman is considered to be of "childbearing potential" if she has had menses at any time in the preceding 12 consecutive months. Exclusion Criteria: * Patients with nodal disease limited to isolated tumour cells (pN0i+ \< 0.2 mm). * Patients with pT3N1 and pT4 disease (Note: patients with T3N0 are eligible). * Any prior history, not including the index cancer, of ipsilateral invasive breast cancer or ipsilateral DCIS treated with radiation therapy. (Patients with synchronous or previous ipsilateral LCIS are eligible.) * Synchronous or previous contralateral invasive breast cancer. (Patients with contralateral DCIS are eligible unless previously treated with radiation.) * History of non-breast malignancies except adequately treated non-melanoma skin cancers, in situ cancers treated by local excision or other cancers curatively treated with no evidence of disease for ≥ 5 years. * Patients who are pregnant. * Patients that have had prior ipsilateral chestwall/thoracic radiation. * Patients treated with chemo or endocrine therapy administered in the neoadjuvant setting for breast cancer. Endocrine therapy exposure 12 weeks or less prior to surgery is permitted. * Patients with serious non-malignant disease (e.g. cardiovascular, scleroderma etc.) which would preclude RT. * Patients with any serious active or co-morbid medical conditions, laboratory abnormality, psychiatric illness, active or uncontrolled infections, or serious illnesses or medical conditions that would prevent the patient from participating or to be managed according to the protocol (according to investigator's decision).

Get updates

Get notified about this study

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer

Contacts and locations

Locations

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Adams Cancer Center

Gettysburg, Pennsylvania, 17325, United States
AdventHealth Littleton

Littleton, Colorado, 80122, United States
AdventHealth Porter

Denver, Colorado, 80210, United States
Advocate Illinois Masonic Medical Center

Chicago, Illinois, 60657, United States
Advocate Lutheran General Hospital

Park Ridge, Illinois, 60068, United States
Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124, United States
Algoma District Cancer Program Sault Area Hospital

Sault Ste. Marie, Ontario, P6B 0A8, Canada
Allan Blair Cancer Centre

Regina, Saskatchewan, S4T 7T1, Canada
Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States
Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704, United States
Altru Cancer Center

Grand Forks, North Dakota, 58201, United States
American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States
Arthur J E Child Comprehensive Cancer Centre

Calgary, Alberta, T2N 5G2, Canada
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Aspirus Cancer Care - James Beck Cancer Center

Rhinelander, Wisconsin, 54501, United States
Aspirus Cancer Care - Stevens Point

Stevens Point, Wisconsin, 54481, United States
Aspirus Cancer Care - Wisconsin Rapids

Wisconsin Rapids, Wisconsin, 54494, United States
Aspirus Regional Cancer Center

Wausau, Wisconsin, 54401, United States
Asplundh Cancer Pavilion

Willow Grove, Pennsylvania, 19090, United States
Atlantic Health Sciences Corporation-Saint John Regional Hospital

Saint John, New Brunswick, E2L 4L2, Canada
Augusta Health Center for Cancer and Blood Disorders

Fishersville, Virginia, 22939, United States
Aultman Health Foundation

Canton, Ohio, 44710, United States
Aurora Bay Area Medical Group-Marinette

Marinette, Wisconsin, 54143, United States
Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311, United States
Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024, United States
Aurora Cancer Care-Kenosha South

Kenosha, Wisconsin, 53142, United States
Aurora Medical Center in Summit

Summit, Wisconsin, 53066, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233, United States
Aurora West Allis Medical Center

West Allis, Wisconsin, 53227, United States
BASS Medical Group - Lennon

Walnut Creek, California, 94598, United States
BCCA-Abbotsford Cancer Centre

Abbotsford British Columbia, British Columbia, V2S 1K2, Canada
BCCA-Cancer Centre for the North

Prince George, British Columbia, V2M 7E9, Canada
BCCA-Cancer Centre for the Southern Interior

Kelowna, British Columbia, V1Y 5L3, Canada
BCCA-Fraser Valley Cancer Centre

Surrey, British Columbia, V3V 1Z2, Canada
BCCA-Vancouver Cancer Centre

Vancouver, British Columbia, V5Z 4E6, Canada
BCCA-Vancouver Island Cancer Centre

Victoria, British Columbia, V8R 6V5, Canada
Banner MD Anderson Cancer Center

Gilbert, Arizona, 85234, United States
Banner North Colorado Medical Center

Greeley, Colorado, 80631, United States
Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539, United States
Banner-University Medical Center Phoenix

Phoenix, Arizona, 85006, United States
Baptist Memorial Hospital and Cancer Center-Desoto

Southhaven, Mississippi, 38671, United States
Baptist Memorial Hospital and Cancer Center-Memphis

Memphis, Tennessee, 38120, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

Houston, Texas, 77030, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Beaufort Memorial/New River Cancer Center

Okatie, South Carolina, 29909, United States
Bellin Memorial Hospital

Green Bay, Wisconsin, 54301, United States
Ben Taub General Hospital

Houston, Texas, 77030, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Boca Raton Regional Hospital

Boca Raton, Florida, 33486, United States
Bon Secours Cancer Institute at Reynolds Crossing

Richmond, Virginia, 23230, United States
Bon Secours Saint Francis Medical Center

Midlothian, Virginia, 23114, United States
Broward Health Medical Center

Fort Lauderdale, Florida, 33316, United States
Bryn Mawr Health Center

Newtown Square, Pennsylvania, 19073, United States
Bryn Mawr Hospital

Bryn Mawr, Pennsylvania, 19010, United States
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)

Québec, Quebec, G1R 2J6, Canada
CHUM - Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
CIUSSSEMTL-Hopital Maisonneuve-Rosemont

Montreal, Quebec, H1T 2M4, Canada
CJW Medical Center - Johnston-Willis Campus

Richmond, Virginia, 23235, United States
CSSS Champlain-Charles Le Moyne

Greenfield Park, Quebec, J4V 2H1, Canada
Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017, United States
CancerCare Manitoba

Winnipeg, Manitoba, R3E 0V9, Canada
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carlisle Regional Cancer Center

Carlisle, Pennsylvania, 17015, United States
CaroMont Regional Medical Center

Gastonia, North Carolina, 28054, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
CentraState Medical Center

Freehold, New Jersey, 07728, United States
Central Vermont Medical Center/National Life Cancer Treatment

Berlin Corners, Vermont, 05602, United States
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont

Sherbrooke, Quebec, J1H 5N4, Canada
Chambersburg Hospital

Chambersburg, Pennsylvania, 17201, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Christiana Care Health System-Concord Health Center

Chadds Ford, Pennsylvania, 19317, United States
City of Hope Antelope Valley

Lancaster, California, 93534, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
City of Hope Corona

Corona, California, 92882, United States
City of Hope South Bay

Torrance, California, 90503, United States
City of Hope South Pasadena

South Pasadena, California, 91030, United States
City of Hope Upland

Upland, California, 91786, United States
City of Hope at Irvine Lennar

Irvine, California, 92618, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Cleveland Clinic Mercy Hospital

Canton, Ohio, 44708, United States
Cleveland Clinic-Weston

Weston, Florida, 33331, United States
Community Cancer Center East

Indianapolis, Indiana, 46219, United States
Community Cancer Center North

Indianapolis, Indiana, 46256, United States
Community Cancer Center South

Indianapolis, Indiana, 46227, United States
Community Medical Center

Missoula, Montana, 59804, United States
Community Medical Center

Toms River, New Jersey, 08755, United States
Corewell Health Beaumont Troy Hospital

Troy, Michigan, 48085, United States
Corewell Health Dearborn Hospital

Dearborn, Michigan, 48124, United States
Corewell Health Farmington Hills Hospital

Farmington Hills, Michigan, 48336, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Corewell Health William Beaumont University Hospital

Royal Oak, Michigan, 48073, United States
Cross Cancer Institute

Edmonton, Alberta, T6G 1Z2, Canada
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Danbury Hospital

Danbury, Connecticut, 06810, United States
Dartmouth Cancer Center - North

Saint Johnsbury, Vermont, 05819, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Delaware Health Center-Grady Cancer Center

Delaware, Ohio, 43015, United States
Desert Regional Medical Center

Palm Springs, California, 92262, United States
Doctor H. Bliss Murphy Cancer Centre

St. John's, Newfoundland and Labrador, A1B 3V6, Canada
Doctor's Hospital of Laredo

Laredo, Texas, 78041, United States
Drexel Town Square Health Center

Oak Creek, Wisconsin, 53154, United States
Dublin Methodist Hospital

Dublin, Ohio, 43016, United States
Duke Cancer Center Cary

Cary, North Carolina, 27518, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Duke Women's Cancer Care Raleigh

Raleigh, North Carolina, 27607, United States
Emory Decatur Hospital

Decatur, Georgia, 30033, United States
Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Englewood Hospital and Medical Center

Englewood, New Jersey, 07631, United States
Ephrata Cancer Center

Ephrata, Pennsylvania, 17522, United States
Exeter Hospital

Exeter, New Hampshire, 03833, United States
Fairbanks Memorial Hospital

Fairbanks, Alaska, 99701, United States
Farmington Health Center

Farmington, Utah, 84025, United States
Forbes Hospital

Monroeville, Pennsylvania, 15146, United States
Fresno Cancer Center

Fresno, California, 93720, United States
Froedtert Menomonee Falls Hospital

Menomonee Falls, Wisconsin, 53051, United States
Froedtert West Bend Hospital/Kraemer Cancer Center

West Bend, Wisconsin, 53095, United States
Geauga Hospital

Chardon, Ohio, 44024, United States
Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651, United States
Good Samaritan Hospital

Corvallis, Oregon, 97330, United States
Grady Health System

Atlanta, Georgia, 30303, United States
Grant Medical Center

Columbus, Ohio, 43215, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States
Greater Regional Medical Center

Creston, Iowa, 50801, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
HSHS Sacred Heart Hospital

Eau Claire, Wisconsin, 54701, United States
HSHS Saint Elizabeth's Hospital

O'Fallon, Illinois, 62269, United States
HSHS Saint Nicholas Hospital

Sheboygan, Wisconsin, 53081, United States
Health Sciences North

Greater Sudbury, Ontario, P3E 5J1, Canada
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Health Providence Novi Hospital

Novi, Michigan, 48374, United States
Henry Ford Health Providence Southfield Hospital

Southfield, Michigan, 48075, United States
Hi-Line Sletten Cancer Center

Havre, Montana, 59501, United States
Highland Hospital

Rochester, New York, 14620, United States
Hope Women's Cancer Centers-Asheville

Asheville, North Carolina, 28816, United States
Hopital de la Cite-de-la-Sante

Laval, Quebec, H7M 3L9, Canada
Houston Methodist Cypress Hospital

Cypress, Texas, 77429, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
Houston Methodist Saint John Hospital

Nassau Bay, Texas, 77058, United States
Houston Methodist San Jacinto Hospital

Baytown, Texas, 77521, United States
Houston Methodist Sugar Land Hospital

Sugar Land, Texas, 77479, United States
Houston Methodist The Woodlands Hospital

The Woodlands, Texas, 77385, United States
Houston Methodist West Hospital

Houston, Texas, 77094, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
IRMC Cancer Center

Indiana, Pennsylvania, 15701, United States
IU Health Ball Memorial Hospital

Muncie, Indiana, 47303, United States
IU Health Central Indiana Cancer Centers-Fishers

Fishers, Indiana, 46037, United States
IU Health Methodist Hospital

Indianapolis, Indiana, 46202, United States
IU Health North Hospital

Carmel, Indiana, 46032, United States
IU Health West Hospital

Avon, Indiana, 46123, United States
Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Ingalls Memorial Hospital

Harvey, Illinois, 60426, United States
Intermountain Health Lutheran Hospital

Wheat Ridge, Colorado, 80401, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Jefferson Hospital

Jefferson Hills, Pennsylvania, 15025, United States
Jefferson Torresdale Hospital

Philadelphia, Pennsylvania, 19114, United States
Jewish General Hospital

Montreal, Quebec, H3T 1E2, Canada
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
Kaiser Permanente Cancer Treatment Center

South San Francisco, California, 94080, United States
Kaiser Permanente Dublin

Dublin, California, 94568, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permanente Oakland-Broadway

Oakland, California, 94611, United States
Kaiser Permanente-Anaheim

Anaheim, California, 92806, United States
Kaiser Permanente-Bellflower

Bellflower, California, 90706, United States
Kaiser Permanente-Ontario

Ontario, California, 91761, United States
Kaiser Permanente-Rancho Cordova Cancer Center

Rancho Cordova, California, 95670, United States
Karmanos Cancer Institute at McLaren Greater Lansing

Lansing, Michigan, 48910, United States
Kent Hospital

Warwick, Rhode Island, 02886, United States
Kingston Health Sciences Centre

Kingston, Ontario, K7L 2V7, Canada
Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854, United States
Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814, United States
LDS Hospital

Salt Lake City, Utah, 84143, United States
LSU Health Sciences Center at Shreveport

Shreveport, Louisiana, 71103, United States
Lafayette Family Cancer Center-EMMC

Brewer, Maine, 04412, United States
Lahey Hospital and Medical Center

Burlington, Massachusetts, 01805, United States
Lancaster General Ann B Barshinger Cancer Institute

Lancaster, Pennsylvania, 17601, United States
Lancaster General Hospital

Lancaster, Pennsylvania, 17602, United States
Langlade Hospital and Cancer Center

Antigo, Wisconsin, 54409, United States
Lankenau Medical Center

Wynnewood, Pennsylvania, 19096, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Lexington Medical Center

West Columbia, South Carolina, 29169, United States
Logan Regional Hospital

Logan, Utah, 84321, United States
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
Lovelace Radiation Oncology

Albuquerque, New Mexico, 87109, United States
Lowell General Hospital

Lowell, Massachusetts, 01854, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Luminis Health Anne Arundel Medical Center

Annapolis, Maryland, 21401, United States
Lutheran Hospital - Cancer Centers of Colorado

Golden, Colorado, 80401, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MD Anderson League City

League City, Texas, 77573, United States
MD Anderson West Houston

Houston, Texas, 77079, United States
MD Anderson in Sugar Land

Sugar Land, Texas, 77478, United States
MD Anderson in The Woodlands

Conroe, Texas, 77384, United States
MU Health - University Hospital/Ellis Fischel Cancer Center

Columbia, Missouri, 65212, United States
MU Health Care Goldschmidt Cancer Center

Jefferson City, Missouri, 65109, United States
Maimonides Medical Center

Brooklyn, New York, 11219, United States
MaineHealth Cancer Care Center of York County

Sanford, Maine, 04073, United States
MaineHealth Coastal Cancer Treatment Center

Bath, Maine, 04530, United States
MaineHealth Maine Medical Center - Portland

Portland, Maine, 04102, United States
MaineHealth Maine Medical Center- Scarborough

Scarborough, Maine, 04074, United States
Margaret R Pardee Memorial Hospital

Hendersonville, North Carolina, 28791, United States
Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Mary Imogene Bassett Hospital

Cooperstown, New York, 13326, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
McLaren Cancer Institute-Bay City

Bay City, Michigan, 48706, United States
McLaren Cancer Institute-Central Michigan

Mount Pleasant, Michigan, 48858, United States
McLaren Cancer Institute-Clarkston

Clarkston, Michigan, 48346, United States
McLaren Cancer Institute-Flint

Flint, Michigan, 48532, United States
McLaren Cancer Institute-Macomb

Mount Clemens, Michigan, 48043, United States
McLaren Cancer Institute-Northern Michigan

Petoskey, Michigan, 49770, United States
McLaren-Port Huron

Port Huron, Michigan, 48060, United States
MedStar Franklin Square Medical Center/Weinberg Cancer Institute

Baltimore, Maryland, 21237, United States
MedStar Georgetown University Hospital

Washington D.C., District of Columbia, 20007, United States
MedStar Good Samaritan Hospital

Baltimore, Maryland, 21239, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Hospital North

Colorado Springs, Colorado, 80920, United States
Memorial Hospital West

Pembroke Pines, Florida, 33028, United States
Memorial Medical Center-Las Cruces

Las Cruces, New Mexico, 88011, United States
Memorial Regional Hospital/Joe DiMaggio Children's Hospital

Hollywood, Florida, 33021, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Mercy Cancer Center - Sacramento

Sacramento, California, 95816, United States
Mercy Cancer Center-Elyria

Elyria, Ohio, 44035, United States
Mercy Cancer Center-West Lakes

Clive, Iowa, 50325, United States
Mercy Health - Perrysburg Hospital

Perrysburg, Ohio, 43551, United States
Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314, United States
Methodist Willowbrook Hospital

Houston, Texas, 77070, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Miami Cancer Institute

Miami, Florida, 33176, United States
Miami Cancer Institute at Plantation

Plantation, Florida, 33324, United States
Miller-Dwan Hospital

Duluth, Minnesota, 55805, United States
Mission Hospital

Asheville, North Carolina, 28801, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467, United States
Montefiore Medical Center-Einstein Campus

The Bronx, New York, 10461, United States
Morton Plant Hospital

Clearwater, Florida, 33756, United States
Mount Carmel Grove City Hospital

Grove City, Ohio, 43123, United States
Mount Sinai Chelsea

New York, New York, 10011, United States
Mount Sinai Hospital

New York, New York, 10029, United States
Mount Sinai Queens

Astoria, New York, 11102, United States
Mount Sinai South Nassau

Oceanside, New York, 11572, United States
Mount Sinai Union Square

New York, New York, 10003, United States
Mount Sinai West

New York, New York, 10019, United States
MultiCare Auburn Medical Center

Auburn, Washington, 98001, United States
MultiCare Gig Harbor Medical Park

Gig Harbor, Washington, 98335, United States
MultiCare Tacoma General Hospital

Tacoma, Washington, 98405, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, 10032, United States
NYU Langone Hospital - Brooklyn

Brooklyn, New York, 11220, United States
NYU Langone Hospital - Long Island

Mineola, New York, 11501, United States
Naval Medical Center - Portsmouth

Portsmouth, Virginia, 23708-2197, United States
New Hampshire Oncology Hematology PA-Concord

Concord, New Hampshire, 03301, United States
New Mexico Oncology Hematology Consultants

Albuquerque, New Mexico, 87109, United States
New York-Presbyterian/Brooklyn Methodist Hospital

Brooklyn, New York, 11215, United States
Niagara Health System-Saint Catharines General

Saint Catharines, Ontario, L2S 0A9, Canada
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026, United States
NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045, United States
Northwestern University

Chicago, Illinois, 60611, United States
Norwalk Hospital

Norwalk, Connecticut, 06856, United States
Noyes Memorial Hospital/Myers Cancer Center

Dansville, New York, 14437, United States
Nyack Hospital

Nyack, New York, 10960, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
Odette Cancer Centre- Sunnybrook Health Sciences Centre

Toronto, Ontario, M4N 3M5, Canada
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
OhioHealth Mansfield Hospital

Mansfield, Ohio, 44903, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Orlando Health Cancer Institute

Orlando, Florida, 32806, United States
Ottawa Hospital and Cancer Center-General Campus

Ottawa, Ontario, K1H 8L6, Canada
Owensboro Health Mitchell Memorial Cancer Center

Owensboro, Kentucky, 42303, United States
Paoli Memorial Hospital

Paoli, Pennsylvania, 19301, United States
Parkland Memorial Hospital

Dallas, Texas, 75235, United States
Penn State Health Saint Joseph Medical Center

Reading, Pennsylvania, 19605, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Pluta Cancer Center

Rochester, New York, 14623, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Prisma Health Cancer Institute - Eastside

Greenville, South Carolina, 29615, United States
Prisma Health Cancer Institute - Faris

Greenville, South Carolina, 29605, United States
Prisma Health Cancer Institute - Greer

Greer, South Carolina, 29650, United States
Prisma Health Cancer Institute - Seneca

Seneca, South Carolina, 29672, United States
Prisma Health Cancer Institute - Spartanburg

Boiling Springs, South Carolina, 29316, United States
ProHealth D N Greenwald Center

Mukwonago, Wisconsin, 53149, United States
ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
Providence Queen of The Valley

Napa, California, 94558, United States
QEII Health Sciences Centre/Nova Scotia Health Authority

Halifax, Nova Scotia, B3H 2Y9, Canada
Radiation Oncology Centers of Nevada Central

Las Vegas, Nevada, 89106, United States
Radiation Oncology Centers of Nevada Southeast

Las Vegas, Nevada, 89119, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Riddle Memorial Hospital

Media, Pennsylvania, 19063, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Riverton Hospital

Riverton, Utah, 84065, United States
Robert Wood Johnson University Hospital Somerset

Somerville, New Jersey, 08876, United States
Rochester General Hospital

Rochester, New York, 14621, United States
Rocky Mountain Cancer Centers-Boulder

Boulder, Colorado, 80304, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Royal Victoria Regional Health Centre

Barrie, Ontario, L4M 6M2, Canada
Rush MD Anderson Cancer Center

Chicago, Illinois, 60612, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Saint Agnes Hospital

Baltimore, Maryland, 21229, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Ann's Hospital

Westerville, Ohio, 43081, United States
Saint Anthony North Hospital

Westminster, Colorado, 80023, United States
Saint Anthony's Hospital Cancer Care Center

St. Petersburg, Florida, 33705, United States
Saint Charles Health System

Bend, Oregon, 97701, United States
Saint Elizabeth Healthcare Edgewood

Edgewood, Kentucky, 41017, United States
Saint Elizabeth Healthcare Fort Thomas

Fort Thomas, Kentucky, 41075, United States
Saint Francis Cancer Center

Colorado Springs, Colorado, 80923, United States
Saint Francis Cancer Center

Greenville, South Carolina, 29607, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint George Regional Medical Center

St. George, Utah, 84770, United States
Saint Helena Hospital

St. Helena, California, 94574, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint John's Cancer Institute

Santa Monica, California, 90404, United States
Saint Joseph Hospital - Orange

Orange, California, 92868, United States
Saint Joseph Hospital East

Lexington, Kentucky, 40509, United States
Saint Joseph Radiation Oncology Resource Center

Lexington, Kentucky, 40504, United States
Saint Joseph's Hospital/Children's Hospital-Tampa

Tampa, Florida, 33607, United States
Saint Joseph's/Candler - Bluffton Campus

Bluffton, South Carolina, 29910, United States
Saint Luke's Hospital

Cedar Rapids, Iowa, 52402, United States
Saint Peter's University Hospital

New Brunswick, New Jersey, 08901, United States
Saint Vincent Hospital

Erie, Pennsylvania, 16544, United States
Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301, United States
Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303, United States
Saint Vincent Hospital Cancer Center at Sturgeon Bay

Sturgeon Bay, Wisconsin, 54235-1495, United States
Sandra L Maxwell Cancer Center

Cedar City, Utah, 84720, United States
Sands Cancer Center

Canandaigua, New York, 14424, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Joe Lueken Cancer Center

Bemidji, Minnesota, 56601, United States
Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States
Saskatoon Cancer Centre

Saskatoon, Saskatchewan, S7N 4H4, Canada
Self Regional Healthcare

Greenwood, South Carolina, 29646, United States
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Sidney Kimmel Cancer Center Washington Township

Sewell, New Jersey, 08080, United States
Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437, United States
Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385, United States
Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611, United States
Smilow Cancer Hospital-Hamden Care Center

Hamden, Connecticut, 06518, United States
Solinsky Center for Cancer Care

Manchester, New Hampshire, 03103, United States
South Jordan Health Center

South Jordan, Utah, 84009, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
State University of New York Upstate Medical University

Syracuse, New York, 13210, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
Suburban Hospital

Bethesda, Maryland, 20814, United States
Sutter Solano Medical Center/Cancer Center

Vallejo, California, 94589, United States
Swedish Covenant Hospital

Chicago, Illinois, 60625, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
The Cancer Institute of New Jersey Hamilton

Hamilton, New Jersey, 08690, United States
The James Graham Brown Cancer Center at University of Louisville

Louisville, Kentucky, 40202, United States
The Mark H Zangmeister Center

Columbus, Ohio, 43219, United States
The Permanente Medical Group-Roseville Radiation Oncology

Roseville, California, 95678, United States
The Radiation Oncology Center-Hilton Head/Bluffton

Hilton Head Island, South Carolina, 29926, United States
The Research Institute of the McGill University Health Centre (MUHC)

Montreal, Quebec, H3H 2R9, Canada
The University of Kansas Cancer Center - Olathe

Olathe, Kansas, 66061, United States
ThedaCare Regional Cancer Center

Appleton, Wisconsin, 54911, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Trillium Health Partners - Credit Valley Hospital

Mississauga, Ontario, L5M 2N1, Canada
Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503, United States
Trinity Health Muskegon Hospital

Muskegon, Michigan, 49444, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868, United States
UC San Diego Health System - Encinitas

Encinitas, California, 92024, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCHealth - Cherry Creek

Denver, Colorado, 80206, United States
UCHealth Greeley Hospital

Greeley, Colorado, 80631, United States
UCHealth Highlands Ranch Hospital

Highlands Ranch, Colorado, 80129, United States
UCHealth Memorial Hospital Central

Colorado Springs, Colorado, 80909, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UChicago Medicine Northwest Indiana

Crown Point, Indiana, 46307, United States
UF Health Cancer Institute - Gainesville

Gainesville, Florida, 32610, United States
UH Seidman Cancer Center at Firelands Regional Medical Center

Sandusky, Ohio, 44870, United States
UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060, United States
UH Seidman Cancer Center at Saint John Medical Center

Westlake, Ohio, 44145, United States
UH Seidman Cancer Center at Southwest General Hospital

Middleburg Heights, Ohio, 44130, United States
UH Seidman Cancer Center at UH Avon Health Center

Avon, Ohio, 44011, United States
UHHS-Chagrin Highlands Medical Center

Beachwood, Ohio, 44122, United States
UHHS-Westlake Medical Center

Westlake, Ohio, 44145, United States
UM Baltimore Washington Medical Center/Tate Cancer Center

Glen Burnie, Maryland, 21061, United States
UM Capital Region Medical Center

Largo, Maryland, 20774, United States
UM Saint Joseph Medical Center

Towson, Maryland, 21204, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables

Coral Gables, Florida, 33146, United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach

Deerfield Beach, Florida, 33442, United States
UM Sylvester Comprehensive Cancer Center at Plantation

Plantation, Florida, 33324, United States
UM Upper Chesapeake Medical Center

Bel Air, Maryland, 21014, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
UPMC Cancer Center - Monroeville

Monroeville, Pennsylvania, 15146, United States
UPMC Cancer Center at UPMC Horizon

Farrell, Pennsylvania, 16121, United States
UPMC Cancer Centers - Arnold Palmer Pavilion

Greensburg, Pennsylvania, 15601, United States
UPMC Hillman Cancer Center Erie

Erie, Pennsylvania, 16505, United States
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion

Mechanicsburg, Pennsylvania, 17050, United States
UPMC Memorial

York, Pennsylvania, 17408, United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus

Harrisburg, Pennsylvania, 17109, United States
UPMC Washington Hospital Radiation Oncology

Washington, Pennsylvania, 15301, United States
UPMC-Johnstown/John P. Murtha Regional Cancer Center

Johnstown, Pennsylvania, 15901, United States
UPMC-Magee Womens Hospital

Pittsburgh, Pennsylvania, 15213, United States
UPMC-Passavant Hospital

Pittsburgh, Pennsylvania, 15237, United States
UPMC-Saint Clair Hospital Cancer Center

Pittsburgh, Pennsylvania, 15243, United States
UPMC-Saint Margaret

Pittsburgh, Pennsylvania, 15215, United States
UPMC-Shadyside Hospital

Pittsburgh, Pennsylvania, 15232, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
UW Health Carbone Cancer Center Rockford

Rockford, Illinois, 61114, United States
University Health Network-Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
University Hospitals Parma Medical Center

Parma, Ohio, 44129, United States
University Hospitals Portage Medical Center

Ravenna, Ohio, 44266, United States
University Hospitals Sharon Health Center

Wadsworth, Ohio, 44281, United States
University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719, United States
University of Arizona Cancer Center-Orange Grove Campus

Tucson, Arizona, 85704, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kansas Cancer Center - Lee's Summit

Lee's Summit, Missouri, 64064, United States
University of Kansas Cancer Center - North

Kansas City, Missouri, 64154, United States
University of Kansas Cancer Center-Overland Park

Overland Park, Kansas, 66210, United States
University of Kansas Health System Saint Francis Campus

Topeka, Kansas, 66606, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Maryland Shore Medical Center at Easton

Easton, Maryland, 21601, United States
University of Maryland/Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Rochester

Rochester, New York, 14642, United States
University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0565, United States
University of Utah Sugarhouse Health Center

Salt Lake City, Utah, 84106, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
University of Virginia Cancer Center

Charlottesville, Virginia, 22908, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center

Madison, Wisconsin, 53718, United States
University of Wisconsin Carbone Cancer Center - Johnson Creek

Johnson Creek, Wisconsin, 53038, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
UofL Health Medical Center Northeast

Louisville, Kentucky, 40245, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241, United States
Waterloo Regional Health Network

Kitchener, Ontario, N2G 1G3, Canada
WellSpan Health-York Cancer Center

York, Pennsylvania, 17403, United States
Wentworth-Douglass Hospital

Dover, New Hampshire, 03820, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
West Penn Hospital

Pittsburgh, Pennsylvania, 15224, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Wexford Health and Wellness Pavilion

Wexford, Pennsylvania, 15090, United States
Wilmot Cancer Institute Radiation Oncology at Greece

Rochester, New York, 14606, United States
Wilmot Cancer Institute at Webster

Webster, New York, 14580, United States
Women and Infants Hospital

Providence, Rhode Island, 02905, United States
Yale University

New Haven, Connecticut, 06520, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.