Could a common ED drug slow Alzheimer's? new trial aims to find out
NCT ID NCT07172815
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 29 times
Summary
This study tests whether tadalafil, a drug used for erectile dysfunction, is safe and might help people with early Alzheimer's or mild memory problems. Researchers will give 244 participants either tadalafil or a placebo daily for one year. They will check for side effects and measure changes in thinking skills and brain function.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tadalafil
What this could lead to
If it works, this could point toward a new way to slow memory loss in early Alzheimer's by improving blood flow in the brain.
What could go wrong
This is a mid-stage trial with only 244 people, so results may not apply to everyone. Tadalafil can cause side effects like headache or upset stomach, and it is not yet proven to help Alzheimer's.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.