Gum recession fix: new platelet-rich fibrin vs. standard graft in head-to-head trial
NCT ID NCT07591142
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two ways to treat receding gums: a new material made from the patient's own blood (T-PRF) and a standard connective tissue graft. Twenty healthy adults with gum recession on both sides of the mouth received both treatments, one on each side. The researchers measured gum coverage, healing, and patient satisfaction over six months to see which worked better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Aug 2025
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Systemically healthy 2. Bilateral gingival recession 3. Good oral hygiene Exclusion Criteria: 1. Smokers 2. Pregnant/lactating women 3. Systemic diseases affecting healing 4. Previous surgery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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School of Dental Medicine
Damascus, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Gum graft surgery: does the bed matter for thin gums?
- Boosting gum grafts: do blood or gel Add-Ons reduce shrinkage?
- Can a new flap technique better cover receding gums?
- Could games and peer support transform orphan dental care?
- A new twist on gum surgery could better cover exposed roots