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Engineered t cells take aim at prostate cancer in early trial

NCT ID NCT01140373

First seen Dec 09, 2025 · Last updated Apr 29, 2026 · Updated 26 times

Summary

This early-phase study tests whether a patient's own immune cells (T cells) can be genetically modified to better recognize and attack prostate cancer cells. The main goal is to check the safety of different doses in men with advanced prostate cancer that no longer responds to hormone therapy. The approach involves removing T cells from the blood, adding a new gene to help them target a protein called PSMA on cancer cells, and infusing them back into the patient.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.