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New obesity drug shows promise in keeping weight off after switching from popular GLP-1 meds

NCT ID NCT07575399

Not yet recruiting Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen May 14, 2026 · Last updated May 18, 2026 · Updated 1 time

Summary

This study tests whether switching from common weight-loss drugs (GLP-1 receptor agonists) to a new medication called maridebart cafraglutide helps adults with obesity or overweight maintain weight loss. About 300 participants who have already lost at least 10% of their body weight on a GLP-1 drug will be switched to the new drug for 68 weeks. The goal is to see if the new drug is safe, tolerable, and effective at keeping weight off.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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