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E-Cigarettes vs. diabetes: a safer smoke?

NCT ID NCT07414355

Knowledge-focused Sponsor: Samsung Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at over 133,000 adults with newly diagnosed type 2 diabetes who were smokers. Researchers wanted to see if switching from regular cigarettes to e-cigarettes could lower the risk of heart problems and diabetes complications. The study used health records to compare outcomes, but did not involve any new treatment or medication.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

133,320 people

The number who actually took part.

Started

Jan 2018

Finished

Dec 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with diabetes from 2018 onward who reported being a "current smoker" at a health examination within the 4 years prior to the diabetes diagnosis, and who could be classified after diagnosis as either continued combustible cigarette smoking ("Current") or e-cigarette use (partial or full transition).

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with diabetes who reported being a "current smoker" at a health examination within the 4 years prior to the diabetes diagnosis. Exclusion Criteria: * age \<40 years or ≥75 years * Pre-existing AMI before diabetes diagnosis * Pre-existing Revascularization before diabetes diagnosis * Pre-existing diabetes complications before diabetes diagnosis * Pre-existing cancer before diabetes diagnosis * Death within 6 months of the first health examination after diabetes diagnosis * Cancer within 6 months of the first health examination after diabetes diagnosis

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Smoking type 2 diabetes mellitus Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clinical outcomes Diabete type 2 E-cigarette use

Contacts and locations

Locations

  • Samsung Medical Center

    Seoul, Gannam-gu, 06351, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.