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Which monitor best predicts fluid response in surgery? new study aims to find out

NCT ID NCT07260890

Diagnosis Sponsor: Wonkwang University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study compares two monitors used during laparoscopic abdominal surgery to see which one better predicts whether giving fluids will help the heart pump more effectively. About 300 adults having elective surgery will receive small fluid boluses, and the monitors' readings will be compared. The goal is to improve how doctors manage fluids during surgery, potentially leading to safer care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors choose the best monitor to guide fluid therapy during surgery, potentially improving patient safety and outcomes.
What could go wrong
This is a single-center diagnostic study, not a treatment trial. The results may not apply to all surgeries or patients, and the monitors may not perform as expected in real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

300 people

The number who actually took part.

Started

Jul 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults undergoing elective laparoscopic major abdominal surgery at a single academic hospital.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * ASA physical status I-III * Elective laparoscopic major abdominal surgery under general anesthesia * Arterial line in place for clinical care * Able to provide informed consent * Arterial and plethysmographic waveforms adequate for measurement Exclusion Criteria: * linically significant arrhythmia (e.g., atrial fibrillation with irregular R-R) * Severe valvular heart disease or intracardiac shunt * Pregnancy * Severe right-heart failure or condition where a fluid bolus is unsafe * Ongoing hemodynamic instability requiring rapid vasoactive titration at assessment * Persistently unreliable arterial/pleth signals despite optimization * Any situation the anesthesiologist judges that the fluid challenge is unsafe

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Conditions

The condition(s) this trial relates to.

Pneumoperitoneum

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fluid therapy Hemodynamics Laparoscopy Monitoring, physiologic Perioperative care

Contacts and locations

Locations

  • Wonkwang University School of Medicine Hospital

    Iksan, Jeollabuk-do, 54538, South Korea

More trials for these conditions

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