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New stitch pattern may prevent dangerous wound opening after colon surgery

NCT ID NCT07585344

Disease control Sponsor: Islamabad Medical and Dental College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different ways of stitching the belly wall closed after colorectal cancer surgery to see which one better prevents the wound from bursting open. Forty adults having open surgery were randomly assigned to either an interrupted 'figure-of-X' stitch or a continuous running stitch. The main goal was to see how many people in each group had a burst abdomen within 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
surgical suturing technique
What this could lead to
If one method proves better, it could reduce serious wound complications after colorectal surgery, leading to faster recovery and fewer reoperations.
What could go wrong
This is a small, single-center study with only 40 patients, so results may not apply to all hospitals or patient groups. The difference between techniques may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Nov 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (aged 18 years and above). * Patients undergoing open laparotomy for histologically confirmed colorectal cancer. * Elective surgical procedures. Exclusion Criteria: * Patients with a previous midline laparotomy within the last 30 days. * Patients in whom the abdominal wall is planned to be left open or managed with a temporary closure (open abdomen). * Patients with known connective tissue disorders (e.g., Ehlers-Danlos syndrome) that might impair wound healing. * Patients with an expected survival of less than 30 days. * Emergency laparotomies.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Surgical Wound Dehiscence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal woumnd dehiscence Burst abdomen Colorectal cancer Surgical site infection

Contacts and locations

Locations

  • Islamabad Medical and Dental College

    Islamabad, Punjab Province, 46000, Pakistan

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