Stitch showdown: which suture heals best after joint replacement?
NCT ID NCT07439575
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways of closing the wound after hip or knee replacement surgery: barbed sutures (a newer type) versus conventional sutures. About 90 adults having hip or knee replacement will be randomly assigned to one method. Researchers will track wound healing, complications like infection, and how well patients recover function over 90 days. The goal is to find which closure technique is safest and most effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If one method proves better, it could lead to faster healing and fewer wound problems after joint replacement surgery.
- What could go wrong
- This is a small, early-stage study (90 people) comparing two common techniques, so results may not apply to all patients or change practice immediately.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 30 years * Patients undergoing primary total hip arthroplasty or total knee arthroplasty * Patients undergoing aseptic revision total hip or knee arthroplasty * Surgery performed by the same surgical team * Ability to provide informed consent Exclusion Criteria: * Age \< 30 years * Patients receiving immunosuppressive therapy * Patients with complicated diabetes mellitus * Chronic venous insufficiency * Peripheral arterial disease * Arthroplasty performed due to malignancy * Active or previous surgical site infection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Umraniye Training and Research Hospital
RECRUITINGIstanbul, Istanbul, 34764, Turkey (Türkiye)
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