New study aims to reduce harmful side effects in rare cancer patients
NCT ID NCT07471425
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will follow 1,100 people with advanced neuroendocrine tumors (a rare, slow-growing cancer) to see which treatments or treatment sequences cause the fewest long-term side effects. Researchers will track patients for up to 5 years, recording any side effects that last more than 6 months. The goal is to create a tool that helps doctors choose the best treatment plan for each patient, balancing effectiveness with quality of life.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2034
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
unresectable or metastatic NET patients
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Unresectable local or metastatic NET naive of treatment tumor except somatostatin analogues or primary surgery. * Unresectable local or metastatic NET newly diagnosed\<6 months whatever the primary NET site * Well differentiated neuroendocrine tumor (WHO classifications) pathologically reviewed locally * No initial medical absolute contraindication to any of the authorized or recommended treatments (no AE\>grade 1 according to NCI CTC v.5 criteria), * Patient who have full medical follow-up in an expert center of the French ENDOCAN network for the management of their advanced neuroendocrine tumor * Patient not opposed to data collection in the on GTE databasis * Patient not opposed to participate in the clinical study Exclusion Criteria: * Patients with severe illness that contraindicates participation to any study * Age \<18 years old
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
14 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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APHM Marseille La Timone
Marseille, 13005, France
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APHP Beaujon
Clichy, 92110, France
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APHP Cochin
Paris, 75014, France
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CHRU Tours
Tours, 37044, France
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CHU Caen
Caen, 14000, France
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CHU Clermont Ferrand
Clermont-Ferrand, 63000, France
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CHU Dijon
Dijon, 21000, France
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CHU Lille
Lille, 59000, France
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CHU Poitiers
Poitiers, 86196, France
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CHU Reims
Reims, 51092, France
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CHU Strasbourg
Strasbourg, 67200, France
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CHU Toulouse
Toulouse, 31300, France
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Centre Eugene Maquis
Rennes, 35000, France
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Hôpital Edouard Herriot
Lyon, 69003, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a targeted drug tame neuroendocrine tumors in everyday practice?
- New hope for rare gut tumors? phase 2 trial launches
- New PET scan could slash radiation by 100x
- Europe-Wide study to settle debate on surgery for spread gut tumors
- New PET scan could slash radiation exposure for tumor patients
- Study to test if patient education improves side effect management for neuroendocrine tumor patients on oral therapy