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New hope for rare gut tumors? phase 2 trial launches

NCT ID NCT07640737

First seen Jun 11, 2026 · Last updated Jun 20, 2026 · Updated 2 times

Summary

This phase 2 trial tests a new drug called AUR103 calcium in 30 people with advanced neuroendocrine tumors that have worsened after at least one prior treatment. The goal is to see if the drug can shrink tumors or stop them from growing. Participants take the drug twice daily until their disease progresses or side effects become too severe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hoag Family Cancer Institute

    Newport Beach, California, 92657, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Cancer Center (MCCC)

    Phoenix, Arizona, 85054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Cancer Center (MCCC)

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Hospital - Florida

    Jacksonville, Florida, 32224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AUR103 calcium

What this could lead to

If successful, this could point toward a new treatment option for people with advanced neuroendocrine tumors that have stopped responding to other therapies.

What could go wrong

This is an early phase 2 proof-of-concept study with only 30 participants. It may not show enough benefit to move forward, and side effects are still being evaluated.

Conditions

The condition(s) this trial relates to.

digestive system neuroendocrine neoplasm digestive system neuroendocrine tumor, grade 1/2 neoplasm neuroendocrine neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.